H₂
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Safety Notes
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reactive oxygen species
774 papers
Delivery-method distribution
hydrogen-rich water: 224
in vitro: 135
inhalation: 133
mixed routes: 118
not specified: 75
injection / infusion: 58
topical application: 14
animal model: 12
hydrogen bath: 5
The unusual cell biology of the hyperthermophilic Crenarchaeon Ignicoccus hospitalis.
2012 ・ Antonie Van Leeuwenhoek ・ PMID 22653377
not specified
not assessed
review
Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.
2012 ・ Arch Oral Biol ・ PMID 22607937
hydrogen-rich water
positive
animal study
Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.
2012 ・ J Neurosci Res ・ PMID 22589232
injection / infusion
positive
animal study
Molecular hydrogen and radiation protection.
2012 ・ Free Radic Res ・ PMID 22537465
mixed routes
positive
review
Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes.
2012 ・ Med Gas Res ・ PMID 22520831
hydrogen-rich water
positive
human randomized controlled trial
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
2012 ・ Shock ・ PMID 22508291
mixed routes
positive
animal study
Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
2012 ・ Hepatology ・ PMID 22505328
hydrogen-rich water
positive
animal study
Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
2012 ・ J Surg Res ・ PMID 22475349
injection / infusion
positive
animal study
Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis.
2012 ・ Med Sci Monit ・ PMID 22460088
injection / infusion
positive
animal study
Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics.
2012 ・ Bioorg Med Chem Lett ・ PMID 22425564
in vitro
positive
in vitro study
Inhalation of hydrogen gas attenuates ouabain-induced auditory neuropathy in gerbils.
2012 ・ Acta Pharmacol Sin ・ PMID 22388074
inhalation
positive
animal study
Hydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated BALB/c mice.
2012 ・ Med Sci Monit ・ PMID 22367121
injection / infusion
positive
animal study
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
2012 ・ Crit Care Med ・ PMID 22336722
inhalation
positive
animal study
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
2012 ・ Cardiovasc Res ・ PMID 22287575
hydrogen-rich water
positive
animal study
Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.
2012 ・ Exp Eye Res ・ PMID 22154552
injection / infusion
positive
animal study
Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ROS and the TNF-α/NF-κB pathway.
2012 ・ Atherosclerosis ・ PMID 22153150
injection / infusion
positive
animal study
Nitrogen deprivation results in photosynthetic hydrogen production in Chlamydomonas reinhardtii.
2012 ・ Planta ・ PMID 22020754
in vitro
not assessed
in vitro study
Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
2012 ・ Biochim Biophys Acta ・ PMID 21621588
mixed routes
not assessed
review
Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
2011 ・ Med Gas Res ・ PMID 22146365
in vitro
positive
in vitro study
Effects of hydrogen-rich water on abnormalities in a SHR.Cg-Leprcp/NDmcr rat - a metabolic syndrome rat model.
2011 ・ Med Gas Res ・ PMID 22146083
hydrogen-rich water
positive
animal study
The 2011 Medical Molecular Hydrogen Symposium: An inaugural symposium of the journal Medical Gas Research.
2011 ・ Med Gas Res ・ PMID 22146082
not specified
not assessed
letter
Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.
2011 ・ Med Gas Res ・ PMID 22146004
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen-rich water attenuates experimental periodontitis in a rat model.
2011 ・ J Clin Periodontol ・ PMID 22092571
hydrogen-rich water
positive
animal study
The Trichomonas vaginalis hydrogenosome proteome is highly reduced relative to mitochondria, yet complex compared with mitosomes.
2011 ・ Int J Parasitol ・ PMID 22079833
in vitro
not assessed
other
Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.
2011 ・ J Physiol Anthropol ・ PMID 21963827
hydrogen-rich water
mixed
animal study
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