日本語View as Markdown

Molecular hydrogen produced by elemental magnesium inhibits rumen fermentation and enhances methanogenesis in dairy cows.

乳牛のルーメン発酵とメタン生成に対する金属マグネシウム由来の分子状水素の影響

animal study animal model mixed

Abstract

A crossover experiment using four non-lactating Holstein dairy cows examined how elevated dissolved H2, generated by dietary elemental magnesium supplementation, influences rumen fermentation and enteric methane production. Compared with Mg(OH)2 supplementation, elemental Mg increased rumen dissolved H2 and methane concentrations at 2.5 hours post-feeding. Feed digestibility and volatile fatty acid concentrations declined, while the acetate-to-propionate ratio and succinate concentration rose. Microbial community analysis revealed reduced abundance of carbohydrate-degrading bacteria (Ruminococcaceae_UCG-014, Bifidobacterium, Mollicutes_RF9) and increased Christensenellaceae and Bacteroidales_BS11. Methanogen populations shifted, with greater abundance of Methanomassiliicoccales and Methanobacteriales and higher 16S rRNA gene copy numbers. These findings indicate that a pulse of dissolved H2 suppresses fermentative bacteria, redirects H2 toward succinate synthesis, and ultimately promotes methanogenesis.

Mechanism

Dissolved H2 generated from elemental Mg suppresses carbohydrate-degrading rumen bacteria, reducing fermentation efficiency. Concurrently, enrichment of Christensenellaceae and Bacteroidales_BS11 channels H2 into succinate production, while expanded methanogen populations (Methanomassiliicoccales, Methanobacteriales) increase H2 utilization for methane synthesis.

Bibliographic

Authors
Ma Z, Zhang XQ, Wang M, Wang R, Jiang Z, Tan Z, et al.
Journal
J Dairy Sci
Year
2019
PMID
30981486
DOI
10.3168/jds.2018-15647

Tags

Mechanism:炎症抑制 ミトコンドリア 酸化ストレス

Delivery context

This study is at the animal-experiment stage. For human application, inhalation is the most promising delivery route, but inhalation carries explosion risk and concentration matters (empirical LFL of 10%; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

Safety notes

This study is at the animal-experiment stage. For human application, inhalation is the most promising delivery route, but inhalation carries explosion risk and concentration matters (empirical LFL of 10%; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

See also:

Cite as: H2 Papers — PMID 30981486. https://h2-papers.org/en/papers/30981486
Source: PubMed PMID 30981486