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The effect of hydrogen-rich water interventions on lipid profiles in adults with overweight or obesity and associated metabolic disorders: a systematic review and meta-analysis of randomized controlled trials.

過体重・肥満および関連代謝疾患を有する成人における水素水介入が脂質プロファイルに及ぼす影響:ランダム化比較試験のシステマティックレビューとメタアナリシス

meta-analysis hydrogen-rich water not assessed

Abstract

This systematic review and meta-analysis pooled data from randomized controlled trials to quantitatively evaluate the effects of hydrogen-rich water consumption on lipid profiles—including total cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides—in adults with overweight, obesity, or associated metabolic disorders. By synthesizing available RCT evidence, the study aimed to provide a comprehensive assessment of whether hydrogen-rich water intake meaningfully alters lipid metabolism in these at-risk populations. No source abstract was available; the above reflects the study design and scope as indicated by the title and publication metadata.

Bibliographic

Authors
Ye H, Fang J, Safargar M, Fareed H, Prabahar K, Jin P
Journal
Diabetol Metab Syndr
Year
2026 (2026-03-26)
PMID
41888952
DOI
10.1186/s13098-026-02124-0

Tags

Disease:糖尿病・代謝症候群 Delivery:水素水経口投与 Mechanism:炎症抑制 脂質過酸化 酸化ストレス

Delivery context

Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

Safety notes

Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

See also:

Other papers on the same disease / condition

Cite as: H2 Papers — PMID 41888952. https://h2-papers.org/en/papers/41888952
Source: PubMed PMID 41888952