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Evidence-based perspective on hydrogen inhalers

Not a product buyer's guide — a literature-anchored view of what to look for when reading the evidence on hydrogen inhalers (concentration band, device design, certifications). See the concentration explainer and the accident-case overview for specifics.

Related papers (7)

• Sixty-minute inhalation of molecular hydrogen decreases blood oxygen saturation but does not alter autonomic cardiac regulation at rest in healthy females: a randomized, double-blind, placebo-controlled crossover study.
  Can J Physiol Pharmacol 2026 — human randomized controlled trial — inhalation — mixed
• Respiratory-physiology modeling of therapeutic hydrogen inhalation: defining the fraction of inspired hydrogen (FiH) and flow-rate requirements.
  Respir Res 2026 — other — inhalation — not assessed
• Performance of Unmodified Mechanical Ventilators With 2% Hydrogen Gas Mixtures.
  Respir Care 2025 — other — inhalation — not assessed
• Hydrogen inhalation: in vivo rat genotoxicity tests.
  Mutat Res Genet Toxicol Environ Mutagen 2024 — animal study — inhalation — null
• Hinhalation therapy in patients with moderate COVID-19 (HCOVID): a prospective ascending-dose phase I clinical trial.
  Antimicrob Agents Chemother 2024 — human case report — inhalation — positive
• Low-Flow Nasal Cannula Hydrogen Therapy.
  J Clin Med Res 2020 — animal study — inhalation — positive
• A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level.
  Med Gas Res 2012 — human case report — inhalation — positive

Related safety notes

• inhalation-concentration
• accident-cases
• lineage