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inhalation delivery
196 papers
Delivery-method distribution
inhalation: 150
mixed routes: 42
not specified: 2
in vitro: 2
Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
2017 ・ Neuroreport ・ PMID 28926473
inhalation
positive
animal study
Molecular hydrogen increases resilience to stress in mice.
2017 ・ Sci Rep ・ PMID 28852144
inhalation
positive
animal study
Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
2017 ・ J Stroke Cerebrovasc Dis ・ PMID 28669654
inhalation
positive
human randomized controlled trial
Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.
2017 ・ Neuroreport ・ PMID 28614179
inhalation
positive
animal study
The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans.
2017 ・ Circ J ・ PMID 28321000
inhalation
mixed
human observational study
[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
2016 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29920028
inhalation
positive
animal study
Molecular hydrogen affords neuroprotection in a translational piglet model of hypoxic-ischemic encephalopathy.
2016 ・ J Physiol Pharmacol ・ PMID 28011948
inhalation
positive
animal study
The Clinical Application of Hydrogen as a Medical Treatment.
2016 ・ Acta Med Okayama ・ PMID 27777424
mixed routes
not assessed
review
Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model.
2016 ・ Exp Ther Med ・ PMID 27284352
inhalation
positive
animal study
Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.
2016 ・ PLoS One ・ PMID 27115738
mixed routes
positive
in vitro study
Molecular hydrogen and catalytic combustion in the production of hyperpolarized 83Kr and 129Xe MRI contrast agents.
2016 ・ Proc Natl Acad Sci U S A ・ PMID 26961001
not specified
not assessed
other
Suppression of ERK phosphorylation through oxidative stress is involved in the mechanism underlying sevoflurane-induced toxicity in the developing brain.
2016 ・ Sci Rep ・ PMID 26905012
inhalation
positive
animal study
Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.
2016 ・ Shock ・ PMID 26849632
inhalation
positive
animal study
Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
2016 ・ Brain Res ・ PMID 26705611
inhalation
positive
animal study
Convenient methods for ingestion of molecular hydrogen: drinking, injection, and inhalation.
safety lineage
2015 ・ Med Gas Res ・ PMID 26504515
mixed routes
not assessed
other
Targeting molecular hydrogen to mitochondria: barriers and gateways.
2015 ・ Pharmacol Res ・ PMID 25720951
not specified
not assessed
review
Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.
2015 ・ Mol Cell Biochem ・ PMID 25707580
mixed routes
positive
animal study
Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
2015 ・ Shock ・ PMID 25643010
inhalation
positive
animal study
[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
inhalation
positive
animal study
Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
2014 ・ Circulation ・ PMID 25366995
inhalation
positive
animal study
Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
2014 ・ Brain Res ・ PMID 25251596
inhalation
positive
animal study
Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
2014 ・ Neurosci Res ・ PMID 25196919
inhalation
positive
animal study
Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes.
2014 ・ Sci Rep ・ PMID 24975958
mixed routes
not assessed
animal study
Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.
2014 ・ Pharmacol Ther ・ PMID 24769081
mixed routes
not assessed
review
Molecular hydrogen consumption in the human body during the inhalation of hydrogen gas.
2013 ・ Adv Exp Med Biol ・ PMID 23852510
inhalation
not assessed
human observational study
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