inhalation delivery

195 papers

• Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.
  2025 ・ BMC Chem ・ PMID 40405232
  inhalation positive animal study
• [Efficiency and safety of the integrated use of medical gases thermal heliox, nitric oxide and molecular hydrogen in patients with exacerbation of chronic obstructive pulmonary disease complicated by hypoxemic, hypercapnic respiratory failure and secondary pulmonary arterial hypertension in the post-COVID period].
  2025 ・ Ter Arkh ・ PMID 40327618
  inhalation positive human randomized controlled trial
• Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption.
  2025 ・ Sci Rep ・ PMID 40181080
  mixed routes positive animal study
• Coral calcium hydride promotes peripheral mitochondrial division and reduces AT-II cells damage in ARDS via activation of the Trx2/Myo19/Drp1 pathway.
  2025 ・ J Pharm Anal ・ PMID 40177064
  mixed routes positive animal study
• Performance of Unmodified Mechanical Ventilators With 2% Hydrogen Gas Mixtures.
  2025 ・ Respir Care ・ PMID 39969918
  inhalation not assessed other
• Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized controlled trial.
  2025 ・ Front Pharmacol ・ PMID 39950118
  inhalation mixed human randomized controlled trial
• Molecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study.
  2025 ・ Med Gas Res ・ PMID 39923133
  inhalation positive human randomized controlled trial
• Evaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice.
  2025 ・ Surgery ・ PMID 39799761
  inhalation positive animal study
• Molecular hydrogen reduces dermatitis-induced itch, diabetic itch and cholestatic itch by inhibiting spinal oxidative stress and synaptic plasticity via SIRT1-β-catenin pathway in mice.
  2025 ・ Redox Biol ・ PMID 39752998
  mixed routes positive animal study
• Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
  2025 ・ Neurochem Int ・ PMID 39653185
  inhalation positive animal study
• Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model.
  2024 ・ Antioxidants (Basel) ・ PMID 39594470
  inhalation positive animal study
• The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension.
  2024 ・ Int J Mol Sci ・ PMID 39456794
  inhalation positive animal study
• Inhalation of H/O(66.7 %/33.3 %) mitigates depression-like behaviors in diabetes mellitus complicated with depression mice via suppressing inflammation and preventing hippocampal damage.
  2024 ・ Biomed Pharmacother ・ PMID 39405908
  inhalation positive animal study
• Molecular Hydrogen and Extracorporeal Gas Exchange: A Match Made in Heaven? An In Vitro Pilot Study.
  2024 ・ Biomedicines ・ PMID 39200347
  in vitro positive in vitro study
• The Landscape of Smart Biomaterial-Based Hydrogen Therapy.
  2024 ・ Adv Sci (Weinh) ・ PMID 39166484
  mixed routes not assessed review
• Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.
  2024 ・ Crit Care Med ・ PMID 39133068
  inhalation mixed human randomized controlled trial
• Realizing brain therapy with "smart medicine": mechanism and case report of molecular hydrogen inhalation for Parkinson's disease.
  2024 ・ Med Gas Res ・ PMID 39073335
  inhalation positive human case report
• Hinhalation therapy in patients with moderate COVID-19 (HCOVID): a prospective ascending-dose phase I clinical trial.
  2024 ・ Antimicrob Agents Chemother ・ PMID 39016593
  inhalation positive human case report
• The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study.
  2024 ・ Free Radic Biol Med ・ PMID 38996821
  inhalation positive human randomized controlled trial
• Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice.
  2024 ・ Biol Res ・ PMID 38915069
  inhalation positive animal study
• Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation.
  2024 ・ J Neurochem ・ PMID 38849977
  inhalation positive animal study
• [Rehabilitation program of post-COVID-19 syndrome with the use of nitric oxide and molecular hydrogen].
  2024 ・ Ter Arkh ・ PMID 38713041
  inhalation positive human randomized controlled trial
• Molecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report.
  2024 ・ In Vivo ・ PMID 38688598
  inhalation positive human case report
• Hydrogen inhalation: in vivo rat genotoxicity tests.
  2024 ・ Mutat Res Genet Toxicol Environ Mutagen ・ PMID 38432775
  inhalation null animal study
• Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy.
  2024 ・ BMC Anesthesiol ・ PMID 38395800
  inhalation positive animal study