H₂
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mitochondrial function
226 papers
Delivery-method distribution
hydrogen-rich water: 55
in vitro: 46
mixed routes: 44
not specified: 34
inhalation: 24
injection / infusion: 15
animal model: 7
hydrogen bath: 1
Design of a minimal di-nickel hydrogenase peptide.
2023 ・ Sci Adv ・ PMID 36897954
in vitro
positive
in vitro study
An NIR-Driven Upconversion/CN/CoP Photocatalyst for Efficient Hydrogen Production by Inhibiting Electron-Hole Pair Recombination for Alzheimer's Disease Therapy.
2023 ・ ACS Nano ・ PMID 36688477
in vitro
positive
animal study
Taurine, Coenzyme Q, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse.
2023 ・ Hear Res ・ PMID 36577362
hydrogen-rich water
positive
animal study
H-induced transient upregulation of phospholipids with suppression of energy metabolism.
2023 ・ Med Gas Res ・ PMID 36571379
in vitro
mixed
in vitro study
The overlooked benefits of hydrogen-producing bacteria.
2023 ・ Med Gas Res ・ PMID 36571374
not specified
not assessed
review
Conventional drug acts as a "rifle gun" while hydrogen as a "machine gun".
2023 ・ Med Gas Res ・ PMID 36204788
not specified
not assessed
review
Molecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic DifferentiationRegulation of Mitochondria.
2023 ・ Curr Stem Cell Res Ther ・ PMID 36165523
in vitro
positive
in vitro study
Effect of water diuresis with hydrogen saturation on the course of acute kidney damage during the separation of oxidation and phosphorylation.
2022 ・ J Med Life ・ PMID 36567846
hydrogen-rich water
positive
animal study
Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
2022 ・ J Transl Med ・ PMID 36435787
injection / infusion
positive
animal study
Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model.
2022 ・ Oxid Med Cell Longev ・ PMID 36199428
hydrogen-rich water
positive
animal study
Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells.
2022 ・ Life Sci ・ PMID 36115583
mixed routes
positive
human observational study
Impact of nutraceuticals and dietary supplements on mitochondria modifications in healthy aging: a systematic review of randomized controlled trials.
2022 ・ Aging Clin Exp Res ・ PMID 35920994
mixed routes
positive
meta-analysis
Narrative on Hydrogen Therapy and its Clinical Applications: Safety and Efficacy.
2022 ・ Curr Pharm Des ・ PMID 35909288
mixed routes
not assessed
review
Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis.
2022 ・ Oxid Med Cell Longev ・ PMID 35528515
in vitro
positive
animal study
Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway.
2022 ・ Biomed Res Int ・ PMID 35528164
mixed routes
positive
in vitro study
Molecular Hydrogen as a Medical Gas for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Possible Efficacy Based on a Literature Review.
2022 ・ Front Neurol ・ PMID 35493814
mixed routes
not assessed
review
The improvement of insulin level after hydrogen-rich water therapy in streptozotocin-induced diabetic rats.
2022 ・ Vet World ・ PMID 35369585
hydrogen-rich water
positive
animal study
Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases.
2022 ・ Oxid Med Cell Longev ・ PMID 35340218
mixed routes
not assessed
review
Emerging Trends and Hot Spots in Sepsis-Associated Encephalopathy Research From 2001 to 2021: A Bibliometric Analysis.
2022 ・ Front Med (Lausanne) ・ PMID 35295600
not specified
not assessed
other
Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
2022 ・ Sci Rep ・ PMID 35273249
mixed routes
positive
animal study
Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response.
2022 ・ Int J Mol Sci ・ PMID 35270030
in vitro
adverse
in vitro study
Attenuation of Myocardial Fibrosis Using Molecular Hydrogen by Inhibiting the TGF-β Signaling Pathway in Spontaneous Hypertensive Rats.
2022 ・ Am J Hypertens ・ PMID 34618887
injection / infusion
positive
animal study
Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer's disease through reducing neuroinflammation and modulating intestinal microbiota.
2022 ・ Neural Regen Res ・ PMID 34269217
hydrogen-rich water
positive
animal study
[Hydrogen-rich water improves progressive sperm motility in rats by reducing oxidative stress and upregulating CLDN3 and SRD5A2 expressions].
2021 ・ Zhonghua Nan Ke Xue ・ PMID 37454313
hydrogen-rich water
positive
animal study
Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives.
2021 ・ Oxid Med Cell Longev ・ PMID 34646423
mixed routes
not assessed
review
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