Nrf2 pathway

106 papers

• Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
  2014 ・ Brain Res ・ PMID 25251596
  inhalation positive animal study
• Hydrogen gas presents a promising therapeutic strategy for sepsis.
  2014 ・ Biomed Res Int ・ PMID 24829918
  inhalation not assessed review
• Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats.
  2014 ・ CNS Neurosci Ther ・ PMID 24685114
  injection / infusion positive animal study
• Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells.
  2014 ・ J Bone Miner Metab ・ PMID 24196871
  in vitro positive in vitro study
• Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
  2013 ・ Free Radic Biol Med ・ PMID 23954468
  hydrogen-rich water positive animal study
• Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases.
  2013 ・ Curr Pharm Des ・ PMID 23859555
  mixed routes not assessed review