Nrf2 pathway

106 papers

• Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
  2019 ・ Int Immunopharmacol ・ PMID 30660872
  inhalation positive animal study
• Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury.
  2019 ・ Can J Physiol Pharmacol ・ PMID 30543459
  injection / infusion positive review
• Inhalation of hydrogen gas elevates urinary 8-hydroxy-2'-deoxyguanine in Parkinson's disease.
  2018 ・ Med Gas Res ・ PMID 30713666
  inhalation null human randomized controlled trial
• Hydrogen-rich water ameliorates rat placental stress induced by water restriction.
  2018 ・ Med Gas Res ・ PMID 30319761
  hydrogen-rich water positive animal study
• Transcriptome analysis of radish sprouts hypocotyls reveals the regulatory role of hydrogen-rich water in anthocyanin biosynthesis under UV-A.
  2018 ・ BMC Plant Biol ・ PMID 30305047
  in vitro positive in vitro study
• Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression.
  2018 ・ Sci Rep ・ PMID 30232347
  injection / infusion positive animal study
• Hydrogen gas inhalation protects against cutaneous ischaemia/reperfusion injury in a mouse model of pressure ulcer.
  2018 ・ J Cell Mol Med ・ PMID 29921037
  inhalation positive animal study
• Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.
  2018 ・ J Surg Res ・ PMID 29907217
  hydrogen-rich water positive animal study
• Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells.
  2018 ・ Int J Mol Med ・ PMID 29532858
  in vitro positive in vitro study
• Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
  2017 ・ Neuroreport ・ PMID 28926473
  inhalation positive animal study
• Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.
  2017 ・ PLoS One ・ PMID 28467497
  in vitro positive in vitro study
• Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical.
  2017 ・ Oxid Med Cell Longev ・ PMID 28243358
  hydrogen-rich water positive animal study
• Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.
  2017 ・ Shock ・ PMID 28234792
  inhalation positive animal study
• Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
  2016 ・ Circ J ・ PMID 27477846
  in vitro positive in vitro study
• Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats.
  2016 ・ Pediatr Pulmonol ・ PMID 26845501
  mixed routes positive animal study
• Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer.
  2016 ・ Biochem Pharmacol ・ PMID 26774456
  hydrogen-rich water positive animal study
• Hydrogen-rich water-alleviated ultraviolet-B-triggered oxidative damage is partially associated with the manipulation of the metabolism of (iso)flavonoids and antioxidant defence in Medicago sativa.
  2015 ・ Funct Plant Biol ・ PMID 32480752
  hydrogen-rich water positive other
• [Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].
  2015 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 27132459
  injection / infusion positive animal study
• Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.
  2015 ・ Med Gas Res ・ PMID 26483953
  mixed routes not assessed review
• Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
  2015 ・ Toxicol Lett ・ PMID 26276082
  in vitro positive in vitro study
• Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
  2015 ・ Chem Biol Interact ・ PMID 26271894
  in vitro positive in vitro study
• Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
  2015 ・ Int Immunopharmacol ・ PMID 26253656
  in vitro positive in vitro study
• Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
  2015 ・ Free Radic Biol Med ・ PMID 26117323
  mixed routes positive animal study
• Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.
  2015 ・ Mol Cell Biochem ・ PMID 25707580
  mixed routes positive animal study
• A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection).
  2014 ・ Med Gas Res ・ PMID 25671079
  not specified not assessed review