H₂
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Safety Notes
日本語
stroke / cerebral ischemia
31 papers
Delivery-method distribution
inhalation: 10
hydrogen-rich water: 8
mixed routes: 7
injection / infusion: 4
not specified: 2
A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection).
2014 ・ Med Gas Res ・ PMID 25671079
not specified
not assessed
review
Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
2013 ・ Free Radic Biol Med ・ PMID 23954468
hydrogen-rich water
positive
animal study
Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.
2012 ・ Brain Res ・ PMID 23010312
injection / infusion
positive
animal study
A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level.
2012 ・ Med Gas Res ・ PMID 22916706
inhalation
positive
human case report
Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.
2012 ・ J Neurosci Res ・ PMID 22589232
injection / infusion
positive
animal study
[Temporary clipping and cerebral blood flow in patients with cerebral aneurysms].
2006 ・ Zh Vopr Neirokhir Im N N Burdenko ・ PMID 17125074
inhalation
not assessed
human observational study
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