最大有酸素速度での疲労困憊走行パフォーマンスに対する運動前水素水摂取の効果：無作為化二重盲検プラセボ対照クロスオーバー試験
This randomized, double-blind, placebo-controlled crossover study enrolled 24 trained male track and field runners (mean age 17.5 years, VO2max 55.0 ml·kg⁻¹·min⁻¹) to examine whether pre-exercise hydrogen-rich water (HRW) ingestion influences exhaustive running capacity. Participants consumed 1260 ml of HRW in four divided doses beginning 120 minutes before exercise. The running protocol included a warm-up, a transition phase, and a final phase at each individual's maximal aerobic speed until exhaustion. Compared with placebo, HRW produced no significant differences in time to exhaustion (217 vs. 227 s, p=0.20), post-exercise blood lactate (9.9 vs. 10.1 mmol·L⁻¹, p=0.42), maximal heart rate (186 vs. 186 beats·min⁻¹, p=0.80), or oxygen uptake (53.1 vs. 52.2 ml·kg⁻¹·min⁻¹, p=0.33). No candidate moderator variable correlated significantly with time to exhaustion. The findings indicate an absence of ergogenic benefit from acute pre-exercise HRW consumption in this population.
No specific mechanistic pathway was investigated in this study; the ergogenic potential of HRW on aerobic running performance was assessed at the physiological outcome level without mechanistic analysis.
Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).
See also:
https://h2-papers.org/en/papers/36538554