Alzheimer's disease

27 papers

• Neuroprotective Effects of Molecular Hydrogen via Oxidative Stress and Neuroinflammation Regulation in a 5xFAD Mouse Model.
  2026 ・ Antioxidants (Basel) ・ PMID 41897548
  inhalation positive animal study
• Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models.
  2025 ・ Int J Mol Sci ・ PMID 40725167
  inhalation positive animal study
• Hydrogen-Bonded Organic Framework-Based NIR-II Activated Hydrogen Production for Treatment of Alzheimer's Disease Model Mice.
  2025 ・ Small ・ PMID 39989154
  in vitro positive animal study
• Molecular hydrogen inhibits neuroinflammation and ameliorates depressive-like behaviors and short-term cognitive impairment in senescence-accelerated mouse prone 8 mice.
  2025 ・ Behav Brain Res ・ PMID 39522774
  hydrogen-rich water positive animal study
• Hydrogen as an innovative nootropic in health and disease.
  2025 ・ Nutr Health ・ PMID 39042916
  mixed routes not assessed review
• Emerging role of antioxidants in Alzheimer's disease: Insight into physiological, pathological mechanisms and management.
  2024 ・ Pharm Sci Adv ・ PMID 41550171
  not specified not assessed review
• Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer's disease: targeting oxidative stress, inflammation, and the gut-brain axis.
  2024 ・ Front Aging Neurosci ・ PMID 39839307
  hydrogen-rich water positive animal study
• Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial.
  2023 ・ Antioxidants (Basel) ・ PMID 37371971
  inhalation positive human observational study
• Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity.
  2023 ・ Antioxidants (Basel) ・ PMID 37237854
  mixed routes not assessed review
• An NIR-Driven Upconversion/CN/CoP Photocatalyst for Efficient Hydrogen Production by Inhibiting Electron-Hole Pair Recombination for Alzheimer's Disease Therapy.
  2023 ・ ACS Nano ・ PMID 36688477
  in vitro positive animal study
• Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders.
  2023 ・ Mol Neurobiol ・ PMID 36567361
  mixed routes not assessed review
• Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation-Fantasy or Reality?
  2022 ・ Int J Mol Sci ・ PMID 35743035
  mixed routes not assessed review
• Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer's disease through reducing neuroinflammation and modulating intestinal microbiota.
  2022 ・ Neural Regen Res ・ PMID 34269217
  hydrogen-rich water positive animal study
• Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model.
  2021 ・ Int J Mol Sci ・ PMID 34948107
  inhalation positive animal study
• Amyloid β structural polymorphism, associated toxicity and therapeutic strategies.
  2021 ・ Cell Mol Life Sci ・ PMID 34643743
  not specified not assessed review
• Montelukast microsuspension with hypromellose for improved stability and oral absorption.
  2021 ・ Int J Biol Macromol ・ PMID 34051251
  not specified positive animal study
• Neuroprotective and Preventative Effects of Molecular Hydrogen.
  2021 ・ Curr Pharm Des ・ PMID 33076798
  hydrogen-rich water not assessed review
• Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.
  2021 ・ Pediatr Res ・ PMID 32505123
  inhalation not assessed review
• Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease.
  2019 ・ Biomaterials ・ PMID 30703744
  injection / infusion positive animal study
• Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.
  2018 ・ Free Radic Res ・ PMID 29683360
  hydrogen-rich water mixed animal study
• Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment.
  2018 ・ Curr Alzheimer Res ・ PMID 29110615
  mixed routes mixed human randomized controlled trial
• Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
  2017 ・ J Clin Biochem Nutr ・ PMID 28751802
  mixed routes not assessed review
• Molecular Hydrogen as a Neuroprotective Agent.
  2017 ・ Curr Neuropharmacol ・ PMID 27281176
  mixed routes not assessed review
• Design and optimization of selective azaindole amide M1 positive allosteric modulators.
  2016 ・ Bioorg Med Chem Lett ・ PMID 26631313
  not specified not assessed other
• Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
  2015 ・ Chem Biol Interact ・ PMID 26271894
  in vitro positive in vitro study