H₂
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antioxidant enzymes
423 papers
Delivery-method distribution
hydrogen-rich water: 179
in vitro: 65
inhalation: 48
mixed routes: 47
injection / infusion: 36
not specified: 30
animal model: 8
topical application: 7
hydrogen bath: 3
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
2018 ・ BMC Cardiovasc Disord ・ PMID 29433438
injection / infusion
positive
animal study
Transplantation of High Hydrogen-Producing Microbiota Leads to Generation of Large Amounts of Colonic Hydrogen in Recipient Rats Fed High Amylose Maize Starch.
2018 ・ Nutrients ・ PMID 29382125
animal model
positive
animal study
Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen-rich saline in gerbil.
2018 ・ Neurosci Lett ・ PMID 29223865
injection / infusion
positive
animal study
The transfer of hydrogen from inert gas to therapeutic gas.
2017 ・ Med Gas Res ・ PMID 29497488
not specified
not assessed
review
Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.
2017 ・ Med Gas Res ・ PMID 29497485
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen-rich water increases postharvest quality by enhancing antioxidant capacity in Hypsizygus marmoreus.
2017 ・ AMB Express ・ PMID 29264772
hydrogen-rich water
positive
other
Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
2017 ・ Mol Clin Oncol ・ PMID 29142752
hydrogen-rich water
positive
human randomized controlled trial
Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation.
2017 ・ PLoS One ・ PMID 28902900
injection / infusion
positive
human observational study
Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.
2017 ・ World J Gastroenterol ・ PMID 28785146
hydrogen-rich water
positive
animal study
Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model.
2017 ・ Med Gas Res ・ PMID 28744362
injection / infusion
positive
animal study
Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells.
2017 ・ Med Gas Res ・ PMID 28744359
in vitro
mixed
in vitro study
Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
2017 ・ Biochem Biophys Res Commun ・ PMID 28743498
in vitro
positive
in vitro study
Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress.
2017 ・ Sci Rep ・ PMID 28620198
in vitro
positive
in vitro study
Hydrogen-rich water alleviates the toxicities of different stresses to mycelial growth in Hypsizygus marmoreus.
2017 ・ AMB Express ・ PMID 28565883
in vitro
positive
in vitro study
Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.
2017 ・ PLoS One ・ PMID 28467497
in vitro
positive
in vitro study
Therapeutic effects of hydrogen on chronic graft-versus-host disease.
2017 ・ J Cell Mol Med ・ PMID 28374556
injection / infusion
positive
animal study
Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention.
2017 ・ Can J Physiol Pharmacol ・ PMID 28350967
injection / infusion
positive
animal study
Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.
2017 ・ World J Gastroenterol ・ PMID 28293084
hydrogen-rich water
positive
animal study
Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical.
2017 ・ Oxid Med Cell Longev ・ PMID 28243358
hydrogen-rich water
positive
animal study
Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.
2017 ・ Shock ・ PMID 28234792
inhalation
positive
animal study
Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.
2017 ・ Nutrients ・ PMID 28098768
hydrogen-rich water
positive
animal study
Proteomic analysis provides insights into the molecular bases of hydrogen gas-induced cadmium resistance in Medicago sativa.
2017 ・ J Proteomics ・ PMID 27989938
hydrogen-rich water
positive
in vitro study
Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
2017 ・ Shock ・ PMID 27918369
hydrogen-rich water
positive
animal study
Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment.
2017 ・ Hum Cell ・ PMID 27804028
in vitro
positive
in vitro study
Hydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage.
2017 ・ J Microbiol Biotechnol ・ PMID 27780950
in vitro
positive
in vitro study
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