apoptosis regulation

280 papers

• Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
  2016 ・ Brain Res ・ PMID 26826009
  injection / infusion positive animal study
• Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.
  2016 ・ Free Radic Biol Med ・ PMID 26709014
  hydrogen-rich water positive animal study
• Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
  2016 ・ Brain Res ・ PMID 26705611
  inhalation positive animal study
• MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis.
  2016 ・ FEBS J ・ PMID 26683671
  mixed routes positive animal study
• Treatment with Hydrogen-Rich Saline Delays Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis.
  2016 ・ Neurochem Res ・ PMID 26537817
  injection / infusion positive animal study
• Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
  2015 ・ Invest Ophthalmol Vis Sci ・ PMID 26720481
  injection / infusion positive animal study
• Discovery of novel quinoline-based mTOR inhibitors via introducing intra-molecular hydrogen bonding scaffold (iMHBS): The design, synthesis and biological evaluation.
  2015 ・ Bioorg Med Chem ・ PMID 26596710
  in vitro positive in vitro study
• Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury.
  2015 ・ J Clin Biochem Nutr ・ PMID 26566302
  hydrogen-rich water positive animal study
• Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
  2015 ・ Toxicol Lett ・ PMID 26276082
  in vitro positive in vitro study
• Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
  2015 ・ Chem Biol Interact ・ PMID 26271894
  in vitro positive in vitro study
• Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
  2015 ・ Int Immunopharmacol ・ PMID 26253656
  in vitro positive in vitro study
• Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
  2015 ・ Free Radic Biol Med ・ PMID 26117323
  mixed routes positive animal study
• Atomic Insight into the Altered O6-Methylguanine-DNA Methyltransferase Protein Architecture in Gastric Cancer.
  2015 ・ PLoS One ・ PMID 26011121
  in vitro not assessed in vitro study
• Michael acceptor in gambogic acid--Its role and application for potent antitumor agents.
  2015 ・ Bioorg Med Chem Lett ・ PMID 26009165
  in vitro mixed in vitro study
• Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.
  2015 ・ Cardiovasc Pathol ・ PMID 25979689
  hydrogen-rich water positive animal study
• Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury.
  2015 ・ Free Radic Res ・ PMID 25947958
  mixed routes positive animal study
• Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.
  2015 ・ Brain Res ・ PMID 25920370
  hydrogen-rich water positive animal study
• Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina.
  2015 ・ Clin Exp Ophthalmol ・ PMID 25801048
  in vitro positive in vitro study
• Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
  2015 ・ Methods Enzymol ・ PMID 25747486
  mixed routes not assessed review
• Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
  2015 ・ Shock ・ PMID 25643010
  inhalation positive animal study
• Molecular hydrogen in sports medicine: new therapeutic perspectives.
  2015 ・ Int J Sports Med ・ PMID 25525953
  mixed routes not assessed review
• Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
  2014 ・ Brain Res ・ PMID 25251596
  inhalation positive animal study
• Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush.
  2014 ・ PLoS One ・ PMID 24915536
  injection / infusion positive animal study
• Hydrogen gas presents a promising therapeutic strategy for sepsis.
  2014 ・ Biomed Res Int ・ PMID 24829918
  inhalation not assessed review
• Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.
  2014 ・ Pharmacol Ther ・ PMID 24769081
  mixed routes not assessed review