-
Mitochondrial dysfunction, neuroinflammation, and associated mechanisms in sepsis-associated encephalopathy: from pathogenesis to emerging therapeutics.
2026 ・ Front Neurosci ・ PMID 42057900
not specified
not assessed
review
-
Neuroprotective Effects of Molecular Hydrogen via Oxidative Stress and Neuroinflammation Regulation in a 5xFAD Mouse Model.
2026 ・ Antioxidants (Basel) ・ PMID 41897548
inhalation
positive
animal study
-
[The combined use of inhaled nitric oxide and molecular hydrogen in patients with post-COVID-19 syndrome].
2026 ・ Ter Arkh ・ PMID 41859790
inhalation
positive
human randomized controlled trial
-
The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.
2026 ・ Eur J Pharmacol ・ PMID 41747800
mixed routes
not assessed
review
-
Hydrogen inhalation is associated with a transient rightward shift in prefrontal oxyhemoglobin asymmetry and autonomic modulation.
2026 ・ Sci Rep ・ PMID 41582106
inhalation
positive
human observational study
-
Medical Gases as Emerging Regulators of Paediatric Endocrine and Neurodevelopmental Pathways: A Mini-Review.
2026 ・ Acta Paediatr ・ PMID 41482991
not specified
not assessed
review
-
Gas Therapies for Neuro-Protection.
2026 ・ Crit Care Clin ・ PMID 41260719
inhalation
not assessed
review
-
A Case Report of Adjuvant Molecular Hydrogen Therapy in Refractory Rheumatoid Arthritis With Atlantoaxial Subluxation.
2025 ・ In Vivo ・ PMID 41167690
not specified
mixed
human case report
-
Molecular hydrogen-rhodiola as an adjuvant therapy for ischemic stroke in internal carotid artery occlusion: A case report.
2025 ・ Open Med (Wars) ・ PMID 41141928
hydrogen-rich water
positive
human case report
-
Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights.
2025 ・ Antioxidants (Basel) ・ PMID 40867844
hydrogen-rich water
positive
animal study
-
Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models.
2025 ・ Int J Mol Sci ・ PMID 40725167
inhalation
positive
animal study
-
Mechanism of hydrogen-rich water alleviating radiation-induced cognitive impairment through PI3K/AKT/Caspase-9 pathway mediating anti-oxidation.
2025 ・ Mol Cell Biochem ・ PMID 40646375
hydrogen-rich water
positive
animal study
-
Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases.
2025 ・ Ageing Res Rev ・ PMID 40518021
mixed routes
not assessed
review
-
Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.
2025 ・ Sci Rep ・ PMID 40410340
hydrogen-rich water
positive
animal study
-
Hydrogen and Methane Detection in Breath in Response to Two Different Types of Dietary Fiber and Its Relationship to Postprandial Glucose Concentration in Obese Patients with Type 2 Diabetes and Normoglycemic Subjects.
2025 ・ Nutrients ・ PMID 40077785
not specified
mixed
human observational study
-
Molecular Hydrogen Therapy Enhances Immune Markers in Treg, Plasma, Tr1 Cells, and KLRG1 Expression on Tc Cells: A Case of Acute SDH With Midline Shift and Uncal Herniation Post-decompressive Craniectomy.
2025 ・ In Vivo ・ PMID 40010997
hydrogen-rich water
mixed
human case report
-
Hydrogen-Bonded Organic Framework-Based NIR-II Activated Hydrogen Production for Treatment of Alzheimer's Disease Model Mice.
2025 ・ Small ・ PMID 39989154
in vitro
positive
animal study
-
Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model.
2025 ・ Antioxidants (Basel) ・ PMID 39857445
hydrogen-rich water
positive
animal study
-
Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
2025 ・ Neurochem Int ・ PMID 39653185
inhalation
positive
animal study
-
Molecular hydrogen inhibits neuroinflammation and ameliorates depressive-like behaviors and short-term cognitive impairment in senescence-accelerated mouse prone 8 mice.
2025 ・ Behav Brain Res ・ PMID 39522774
hydrogen-rich water
positive
animal study
-
Hydrogen as an innovative nootropic in health and disease.
2025 ・ Nutr Health ・ PMID 39042916
mixed routes
not assessed
review
-
Emerging role of antioxidants in Alzheimer's disease: Insight into physiological, pathological mechanisms and management.
2024 ・ Pharm Sci Adv ・ PMID 41550171
not specified
not assessed
review
-
Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer's disease: targeting oxidative stress, inflammation, and the gut-brain axis.
2024 ・ Front Aging Neurosci ・ PMID 39839307
hydrogen-rich water
positive
animal study
-
New possibilities of the prevention and treatment of cardiovascular pathologies. the potential of molecular hydrogen in the reduction of oxidative stress and its consequences.
2024 ・ Physiol Res ・ PMID 39808170
not specified
not assessed
review
-
Molecular Hydrogen Therapy in Aneurysmal SAH With RA and Newly-diagnosed SLE, Complicated With Acute Ischemic Infarction: A Case Report of Improved Immune Markers Including Tr1 Cells, Breg Cells and TIM3 Expression on Tc Cells.
2024 ・ In Vivo ・ PMID 39477420
hydrogen-rich water
positive
human case report