H₂
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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
2020 ・ Prog Neuropsychopharmacol Biol Psychiatry ・ PMID 31629777
injection / infusion
positive
animal study
A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.
2020 ・ Can J Physiol Pharmacol ・ PMID 31536712
hydrogen-rich water
positive
animal study
Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection.
2019 ・ Ann Transl Med ・ PMID 32042790
inhalation
positive
animal study
Molecular hydrogen: current knowledge on mechanism in alleviating free radical damage and diseases.
2019 ・ Acta Biochim Biophys Sin (Shanghai) ・ PMID 31738389
not specified
not assessed
review
Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.
2019 ・ PLoS One ・ PMID 31574107
injection / infusion
positive
animal study
Effect of Htreatment in a mouse model of rheumatoid arthritis-associated interstitial lung disease.
2019 ・ J Cell Mol Med ・ PMID 31424157
hydrogen-rich water
positive
animal study
Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment.
2019 ・ Front Pharmacol ・ PMID 31396089
hydrogen-rich water
positive
animal study
Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction.
2019 ・ Can J Physiol Pharmacol ・ PMID 31295412
in vitro
positive
in vitro study
Effects of hydrogen-rich water on the nutrient composition and antioxidative characteristics of sprouted black barley.
2019 ・ Food Chem ・ PMID 31279124
hydrogen-rich water
positive
in vitro study
Micro/Nanomaterials-Augmented Hydrogen Therapy.
2019 ・ Adv Healthc Mater ・ PMID 31267691
mixed routes
not assessed
review
Circulating messenger for neuroprotection induced by molecular hydrogen.
2019 ・ Can J Physiol Pharmacol ・ PMID 31100203
hydrogen-rich water
not assessed
review
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
2019 ・ Mol Med Rep ・ PMID 31059036
animal model
positive
animal study
Therapeutic Efficacy of Molecular Hydrogen: A New Mechanistic Insight.
2019 ・ Curr Pharm Des ・ PMID 31057105
not specified
not assessed
review
The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved.
2019 ・ Free Radic Res ・ PMID 30773939
mixed routes
not assessed
review
Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
2019 ・ BMC Gastroenterol ・ PMID 30736744
injection / infusion
positive
animal study
Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease.
2019 ・ Biomaterials ・ PMID 30703744
injection / infusion
positive
animal study
The Effect of Gold Nanoparticle Concentration and Laser Fluence on the Laser-Induced Water Decomposition.
2019 ・ J Phys Chem B ・ PMID 30696249
in vitro
not assessed
in vitro study
Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
2019 ・ Int Immunopharmacol ・ PMID 30660872
inhalation
positive
animal study
Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury.
2019 ・ Can J Physiol Pharmacol ・ PMID 30543459
injection / infusion
positive
review
Hydrogen gas reduces chronic intermittent hypoxia-induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation.
2019 ・ J Cell Biochem ・ PMID 30259991
inhalation
positive
animal study
Inhalation of hydrogen gas elevates urinary 8-hydroxy-2'-deoxyguanine in Parkinson's disease.
2018 ・ Med Gas Res ・ PMID 30713666
inhalation
null
human randomized controlled trial
[Hydrogen rich water attenuates pregnancy gingivitis induced by ligation in SD rats].
2018 ・ Shanghai Kou Qiang Yi Xue ・ PMID 30411118
hydrogen-rich water
positive
animal study
Molecular hydrogen may enhance the production of testosterone hormone in male infertility through hormone signal modulation and redox balance.
2018 ・ Med Hypotheses ・ PMID 30396494
not specified
not assessed
other
Hydrogen molecules (H2) improve perfusion recovery via antioxidant effects in experimental peripheral arterial disease.
2018 ・ Mol Med Rep ・ PMID 30320393
hydrogen-rich water
positive
animal study
Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.
2018 ・ Liver Transpl ・ PMID 30120877
injection / infusion
positive
animal study
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