H₂
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
An NIR-Driven Upconversion/CN/CoP Photocatalyst for Efficient Hydrogen Production by Inhibiting Electron-Hole Pair Recombination for Alzheimer's Disease Therapy.
2023 ・ ACS Nano ・ PMID 36688477
in vitro
positive
animal study
H-induced transient upregulation of phospholipids with suppression of energy metabolism.
2023 ・ Med Gas Res ・ PMID 36571379
in vitro
mixed
in vitro study
The overlooked benefits of hydrogen-producing bacteria.
2023 ・ Med Gas Res ・ PMID 36571374
not specified
not assessed
review
Two-Dimensional MgSi Nanosheet-Enabled Sustained Hydrogen Generation for Improved Repair and Regeneration of Deeply Burned Skin.
2023 ・ Adv Healthc Mater ・ PMID 36546774
topical application
positive
in vitro study
Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
2023 ・ Int Immunopharmacol ・ PMID 36538853
inhalation
positive
animal study
Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
2023 ・ Brain Res Bull ・ PMID 36516898
mixed routes
positive
human observational study
Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids.
2023 ・ Dig Dis Sci ・ PMID 36478314
hydrogen-rich water
positive
animal study
Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
2023 ・ CNS Neurosci Ther ・ PMID 36468415
mixed routes
positive
animal study
Conventional drug acts as a "rifle gun" while hydrogen as a "machine gun".
2023 ・ Med Gas Res ・ PMID 36204788
not specified
not assessed
review
Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury.
2023 ・ Med Gas Res ・ PMID 36204787
inhalation
positive
animal study
Molecular hydrogen exposure improves functional state of red blood cells in the early postoperative period: a randomized clinical study.
2023 ・ Med Gas Res ・ PMID 36204784
inhalation
positive
human randomized controlled trial
Molecular Hydrogen Promotes Adipose-derived Stem Cell Myogenic DifferentiationRegulation of Mitochondria.
2023 ・ Curr Stem Cell Res Ther ・ PMID 36165523
in vitro
positive
in vitro study
Hydrogen Gas Inhalation Attenuates Acute Impulse Noise Trauma: A Preclinical In Vivo Study.
2023 ・ Ann Otol Rhinol Laryngol ・ PMID 35962590
inhalation
positive
animal study
Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway.
2023 ・ J Neuroimmune Pharmacol ・ PMID 35895245
inhalation
positive
animal study
[Alleviating effects of hydrogen on hyperhomocysteinemia and fatty liver induced by high-methionine diet].
2022 ・ Zhongguo Ying Yong Sheng Li Xue Za Zhi ・ PMID 37308436
hydrogen-rich water
positive
animal study
Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
2022 ・ PLoS One ・ PMID 36574398
injection / infusion
positive
animal study
Effect of water diuresis with hydrogen saturation on the course of acute kidney damage during the separation of oxidation and phosphorylation.
2022 ・ J Med Life ・ PMID 36567846
hydrogen-rich water
positive
animal study
New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice.
2022 ・ Antioxidants (Basel) ・ PMID 36552595
hydrogen-rich water
positive
animal study
The effects of hydrogen treatment in a cigarette smoke solution-induced chronic obstructive pulmonary disease-like changes in an animal model.
2022 ・ J Thorac Dis ・ PMID 36524091
inhalation
positive
animal study
Electrolyzed-Reduced Water: Review II: Safety Concerns and Effectiveness as a Source of Hydrogen Water.
2022 ・ Int J Mol Sci ・ PMID 36498838
hydrogen-rich water
mixed
review
Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
2022 ・ J Transl Med ・ PMID 36435787
injection / infusion
positive
animal study
Effects of hydrogen rich water and pure water on periodontal inflammatory factor level, oxidative stress level and oral flora: a systematic review and meta-analysis.
2022 ・ Ann Transl Med ・ PMID 36388830
hydrogen-rich water
positive
meta-analysis
Treatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice.
2022 ・ Antioxidants (Basel) ・ PMID 36358525
injection / infusion
positive
animal study
Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.
2022 ・ Vet Sci ・ PMID 36356098
hydrogen-rich water
positive
animal study
Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial.
2022 ・ Antioxidants (Basel) ・ PMID 36290657
hydrogen-rich water
mixed
human randomized controlled trial
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