H₂
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mitochondrial function
226 papers
Delivery-method distribution
hydrogen-rich water: 55
in vitro: 46
mixed routes: 44
not specified: 34
inhalation: 24
injection / infusion: 15
animal model: 7
hydrogen bath: 1
Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities.
2019 ・ Pharmacol Res ・ PMID 31509764
not specified
not assessed
review
Effects of the Photosystem II Inhibitors CCCP and DCMU on Hydrogen Production by the Unicellular Halotolerant Cyanobacterium.
2019 ・ ScientificWorldJournal ・ PMID 31346323
in vitro
positive
in vitro study
Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction.
2019 ・ Can J Physiol Pharmacol ・ PMID 31295412
in vitro
positive
in vitro study
Micro/Nanomaterials-Augmented Hydrogen Therapy.
2019 ・ Adv Healthc Mater ・ PMID 31267691
mixed routes
not assessed
review
Therapeutic Efficacy of Molecular Hydrogen: A New Mechanistic Insight.
2019 ・ Curr Pharm Des ・ PMID 31057105
not specified
not assessed
review
Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial.
2019 ・ Clin Res Hepatol Gastroenterol ・ PMID 30982748
hydrogen-rich water
positive
human randomized controlled trial
Molecular hydrogen produced by elemental magnesium inhibits rumen fermentation and enhances methanogenesis in dairy cows.
2019 ・ J Dairy Sci ・ PMID 30981486
animal model
mixed
animal study
Hydrogen gas: from clinical medicine to an emerging ergogenic molecule for sports athletes.
2019 ・ Can J Physiol Pharmacol ・ PMID 30970215
mixed routes
not assessed
review
Acid-Responsive H-Releasing 2D MgBNanosheet for Therapeutic Synergy and Side Effect Attenuation of Gastric Cancer Chemotherapy.
2019 ・ Adv Healthc Mater ・ PMID 30968583
mixed routes
positive
animal study
The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved.
2019 ・ Free Radic Res ・ PMID 30773939
mixed routes
not assessed
review
Sustained release of bioactive hydrogen by Pd hydride nanoparticles overcomes Alzheimer's disease.
2019 ・ Biomaterials ・ PMID 30703744
injection / infusion
positive
animal study
FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.
2019 ・ Behav Brain Res ・ PMID 29885845
hydrogen-rich water
positive
animal study
Quantitative proteomics reveals the mechanisms of hydrogen-conferred protection against hyperoxia-induced injury in type II alveolar epithelial cells.
2018 ・ Exp Lung Res ・ PMID 30973277
in vitro
positive
in vitro study
Effects of alkaline-electrolyzed and hydrogen-rich water, in a high-fat-diet nonalcoholic fatty liver disease mouse model.
2018 ・ World J Gastroenterol ・ PMID 30568387
hydrogen-rich water
mixed
animal study
Reaction Mechanism of [NiFe] Hydrogenase Studied by Computational Methods.
2018 ・ Inorg Chem ・ PMID 30500163
not specified
not assessed
other
Molecular hydrogen may enhance the production of testosterone hormone in male infertility through hormone signal modulation and redox balance.
2018 ・ Med Hypotheses ・ PMID 30396494
not specified
not assessed
other
Protective effects of hydrogen gas against sepsis-induced acute lung injury via regulation of mitochondrial function and dynamics.
2018 ・ Int Immunopharmacol ・ PMID 30380511
inhalation
positive
animal study
Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
2018 ・ Front Physiol ・ PMID 30108516
inhalation
positive
animal study
Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.
2018 ・ Sci Rep ・ PMID 29907804
animal model
positive
animal study
Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitats.
2018 ・ ISME J ・ PMID 29849169
in vitro
not assessed
other
[Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury].
2018 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29663991
injection / infusion
positive
animal study
Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women.
2018 ・ Ir J Med Sci ・ PMID 28560519
hydrogen-rich water
mixed
human randomized controlled trial
Molecular hydrogen generated by elemental magnesium supplementation alters rumen fermentation and microbiota in goats.
2017 ・ Br J Nutr ・ PMID 28927478
animal model
mixed
animal study
Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.
2017 ・ Biochem Biophys Res Commun ・ PMID 28890349
animal model
positive
animal study
Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
2017 ・ Biochem Biophys Res Commun ・ PMID 28743498
in vitro
positive
in vitro study
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