Nrf2 pathway

106 papers

• Mitochondrial dysfunction, neuroinflammation, and associated mechanisms in sepsis-associated encephalopathy: from pathogenesis to emerging therapeutics.
  2026 ・ Front Neurosci ・ PMID 42057900
  not specified not assessed review
• Hydrogen gas inhalation alleviated cerebral ischemia/reperfusion injury by regulating mitophagy in SH-SY5Y cells and mice via PTEN-induced kinase 1/Parkin pathway.
  2026 ・ J Stroke Cerebrovasc Dis ・ PMID 42049119
  inhalation positive animal study
• Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms.
  2026 ・ Int J Mol Sci ・ PMID 41977237
  hydrogen-rich water positive animal study
• Neuroprotective Effects of Molecular Hydrogen via Oxidative Stress and Neuroinflammation Regulation in a 5xFAD Mouse Model.
  2026 ・ Antioxidants (Basel) ・ PMID 41897548
  inhalation positive animal study
• Comparison of hydrogen administration methods in the treatment of radiation-induced heart disease in rats.
  2026 ・ Can J Physiol Pharmacol ・ PMID 41806364
  mixed routes positive animal study
• Transcriptome-Based Evaluation of Hydrogen Gas Effects for Preventing UVA-Induced Photoaging Using an Artificial Skin Model.
  2026 ・ Geriatr Gerontol Int ・ PMID 41749059
  in vitro positive in vitro study
• Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice.
  2026 ・ Int J Mol Sci ・ PMID 41596287
  mixed routes positive animal study
• Medical Gases as Emerging Regulators of Paediatric Endocrine and Neurodevelopmental Pathways: A Mini-Review.
  2026 ・ Acta Paediatr ・ PMID 41482991
  not specified not assessed review
• Osteoimmunometabolic modulation via hydrogen-self-supplying magnesium-reinforced collagen membrane for enhanced guided bone regeneration.
  2026 ・ Biomaterials ・ PMID 41435455
  in vitro positive animal study
• Hydrogen gas promotes neuroprotection and upregulates ATF5 expression in neonatal hypoxic-ischemic brain injury.
  2026 ・ Exp Neurol ・ PMID 41386344
  inhalation positive animal study
• Hydrogen intervention attenuates chronic hypoxia-induced bone degeneration and multi-organ damage via modulation of the gut microbiota.
  2026 ・ Bone ・ PMID 41224067
  hydrogen-rich water positive animal study
• Mechanism by which hydrogen-rich water mitigates exercise-induced fatigue: activation of the immunoresponsive gene 1-itaconate/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway.
  2026 ・ Med Gas Res ・ PMID 40580185
  hydrogen-rich water positive animal study
• Molecular Hydrogen Affords Similar Neuroprotection to Therapeutic Hypothermia in a Porcine Model of Neonatal Hypoxic-Ischemic Encephalopathy.
  2025 ・ Antioxidants (Basel) ・ PMID 41462605
  inhalation positive animal study
• Synergistic alleviation effects of salt-tolerant plant growth-promoting rhizobacteria and hydrogen-rich water on salt stress in.
  2025 ・ Front Plant Sci ・ PMID 41234312
  hydrogen-rich water positive other
• Gut microbiota as a central mediator in hydrogen gas-induced alleviation of colitis via TLR4/NF-κB and Nrf2 pathway regulation.
  2025 ・ Int Immunopharmacol ・ PMID 41076929
  inhalation positive animal study
• Nanobiocatalyst-Driven Spatiotemporal Hydrogen Delivery Induces Dormancy Potentiated Catalytic Tumor Therapy.
  2025 ・ ACS Nano ・ PMID 40931918
  in vitro positive in vitro study
• Preventing Cisplatin-Induced Neuropathy and Related Emotional Disorders with the Coadministration of Duloxetine and Hydrogen-Rich Water in Male and Female Mice.
  2025 ・ Antioxidants (Basel) ・ PMID 40867900
  mixed routes positive animal study
• Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights.
  2025 ・ Antioxidants (Basel) ・ PMID 40867844
  hydrogen-rich water positive animal study
• Hydrogen promoted mitochondrial autophagy and alleviated CIH-induced vascular endothelial cell senescence by regulating oxidative stress.
  2025 ・ Eur J Pharmacol ・ PMID 40845957
  animal model positive animal study
• Acid-triggered ultralong hydrogen release from AB-loaded hollow mesoporous silica nanoparticles enhances salt tolerance in sweetpotato.
  2025 ・ J Biotechnol ・ PMID 40651661
  in vitro positive other
• Redox reactions in chronic pain: mechanisms and relevance in fibromyalgia.
  2025 ・ Front Pain Res (Lausanne) ・ PMID 40432823
  not specified not assessed review
• Role and mechanism of molecular hydrogen in the treatment of Parkinson's diseases.
  2025 ・ Front Neurosci ・ PMID 40336538
  mixed routes mixed review
• Advanced Glycation End Products and Skin Autoimmune Disorders: Pathogenic Insights into Vitiligo, Bullous Pemphigoid, and Type 1 Diabetes Mellitus.
  2025 ・ Curr Med Chem ・ PMID 40289982
  hydrogen-rich water not assessed review
• The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
  2025 ・ Life Sci Space Res (Amst) ・ PMID 40280637
  hydrogen-rich water positive animal study
• Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.
  2025 ・ Clin Cosmet Investig Dermatol ・ PMID 40061044
  mixed routes not assessed review