Nrf2 pathway

106 papers

• Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.
  2025 ・ PLoS One ・ PMID 39951412
  hydrogen-rich water positive animal study
• Molecular hydrogen reduces dermatitis-induced itch, diabetic itch and cholestatic itch by inhibiting spinal oxidative stress and synaptic plasticity via SIRT1-β-catenin pathway in mice.
  2025 ・ Redox Biol ・ PMID 39752998
  mixed routes positive animal study
• Synergistic Antioxidant Effects of Molecular Hydrogen and Cold Atmospheric Plasma in Enhancing Mesenchymal Stem Cell Therapy.
  2024 ・ Antioxidants (Basel) ・ PMID 39765910
  mixed routes not assessed review
• Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells.
  2024 ・ Biomedicines ・ PMID 39062020
  in vitro positive in vitro study
• The Combination of Molecular Hydrogen and Heme Oxygenase 1 Effectively Inhibits Neuropathy Caused by Paclitaxel in Mice.
  2024 ・ Antioxidants (Basel) ・ PMID 39061924
  hydrogen-rich water positive animal study
• Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.
  2024 ・ J Cell Mol Med ・ PMID 39001579
  hydrogen-rich water positive animal study
• Hydrogen nanobubbles and oxidative windows: Investigating how varying hydrogen concentrations influence seed germination and stress defense.
  2024 ・ J Hazard Mater ・ PMID 38941838
  hydrogen-rich water mixed in vitro study
• A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease.
  2024 ・ Antioxidants (Basel) ・ PMID 38929185
  animal model positive animal study
• Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice.
  2024 ・ Biol Res ・ PMID 38915069
  inhalation positive animal study
• Hydrogen-rich water alleviates constipation by attenuating oxidative stress through the sirtuin1/nuclear factor-erythroid-2-related factor 2/heme oxygenase-1 signaling pathway.
  2024 ・ World J Gastroenterol ・ PMID 38855154
  hydrogen-rich water positive animal study
• Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease.
  2024 ・ Biomed Pharmacother ・ PMID 38795643
  mixed routes not assessed review
• The role of hydrogen in the prevention and treatment of coronary atherosclerotic heart disease.
  2024 ・ Eur J Pharmacol ・ PMID 38615891
  not specified not assessed review
• Decoupling the mutual promotion of inflammation and oxidative stress mitigates cognitive decline and depression-like behavior in rmTBI mice by promoting myelin renewal and neuronal survival.
  2024 ・ Biomed Pharmacother ・ PMID 38479178
  hydrogen-rich water positive animal study
• Hydrogen-rich water: a key player in boosting wheat (Triticum aestivum L.) seedling growth and drought resilience.
  2023 ・ Sci Rep ・ PMID 38110488
  hydrogen-rich water positive other
• Therapeutic Potential of Hydrogen-Rich Water on Muscle Atrophy Caused by Immobilization in a Mouse Model.
  2023 ・ Pharmaceuticals (Basel) ・ PMID 37895907
  hydrogen-rich water positive animal study
• Molecular hydrogen: prospective treatment strategy of kidney damage after cardiac surgery.
  2023 ・ Can J Physiol Pharmacol ・ PMID 37463517
  inhalation positive animal study
• Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway.
  2023 ・ J Neuroimmune Pharmacol ・ PMID 35895245
  inhalation positive animal study
• New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36552595
  hydrogen-rich water positive animal study
• Treatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36358525
  injection / infusion positive animal study
• Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.
  2022 ・ Vet Sci ・ PMID 36356098
  hydrogen-rich water positive animal study
• Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial.
  2022 ・ Antioxidants (Basel) ・ PMID 36290657
  hydrogen-rich water mixed human randomized controlled trial
• Hydrogen-Rich Water as a Novel Therapeutic Strategy for the Affective Disorders Linked with Chronic Neuropathic Pain in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36139900
  hydrogen-rich water positive animal study
• Transcriptome and Metabonomics Combined Analysis Revealed the Defense Mechanism Involved in Hydrogen-Rich Water-Regulated Cold Stress Response of.
  2022 ・ Front Plant Sci ・ PMID 35812920
  hydrogen-rich water positive other
• Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases.
  2022 ・ Oxid Med Cell Longev ・ PMID 35340218
  mixed routes not assessed review
• The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs.
  2021 ・ Vet Sci ・ PMID 34822637
  hydrogen-rich water positive animal study