H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities.
2021 ・ Curr Pharm Des ・ PMID 32962610
mixed routes
positive
review
Oxidative Stress and Pathways of Molecular Hydrogen Effects in Medicine.
2021 ・ Curr Pharm Des ・ PMID 32954996
not specified
not assessed
review
Molecular Hydrogen Application in Stroke: Bench to Bedside.
2021 ・ Curr Pharm Des ・ PMID 32940172
mixed routes
not assessed
review
Perspective of Molecular Hydrogen in the Treatment of Sepsis.
2021 ・ Curr Pharm Des ・ PMID 32912119
mixed routes
not assessed
review
Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions.
2021 ・ Curr Pharm Des ・ PMID 32767925
not specified
not assessed
review
Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.
2021 ・ Ann Thorac Surg ・ PMID 32649946
injection / infusion
positive
animal study
Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
2021 ・ Shock ・ PMID 32590694
inhalation
positive
animal study
Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.
2021 ・ Pediatr Res ・ PMID 32505123
inhalation
not assessed
review
Inhaled Gases as Therapies for Post-Cardiac Arrest Syndrome: A Narrative Review of Recent Developments.
2020 ・ Front Med (Lausanne) ・ PMID 33585501
inhalation
not assessed
review
Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.
2020 ・ Int J Mol Sci ・ PMID 33419292
topical application
positive
human observational study
Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study.
2020 ・ Med Gas Res ・ PMID 33380582
hydrogen-rich water
mixed
human randomized controlled trial
Impact of hydrogen-rich gas mixture inhalation through nasal cannula during post-exercise recovery period on subsequent oxidative stress, muscle damage, and exercise performances in men.
2020 ・ Med Gas Res ・ PMID 33380581
inhalation
mixed
human randomized controlled trial
Magnesium Hydride-Mediated Sustainable Hydrogen Supply Prolongs the Vase Life of Cut Carnation Flowers via Hydrogen Sulfide.
2020 ・ Front Plant Sci ・ PMID 33362825
in vitro
positive
other
Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems.
2020 ・ Antioxidants (Basel) ・ PMID 33333951
mixed routes
not assessed
review
Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial.
2020 ・ Front Immunol ・ PMID 33324415
hydrogen-rich water
positive
human observational study
Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension.
2020 ・ Sci Rep ・ PMID 33244027
inhalation
positive
animal study
The Long-Term Effect of Medically Enhancing Melanin Intrinsic Bioenergetics Capacity in Prematurity.
2020 ・ Curr Genomics ・ PMID 33214768
not specified
not assessed
review
Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients.
2020 ・ Front Pharmacol ・ PMID 33178011
inhalation
not assessed
review
The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report.
2020 ・ Cent Nerv Syst Agents Med Chem ・ PMID 33167844
topical application
mixed
human case report
The Effects of Supersaturated Hydrogen-Rich Water Bathing on Biomarkers of Muscular Damage and Soreness Perception in Young Men Subjected to High-Intensity Eccentric Exercise.
2020 ・ J Sports Med (Hindawi Publ Corp) ・ PMID 33123594
hydrogen bath
positive
human randomized controlled trial
Effects of long-term hydrogen intervention on the physiological function of rats.
2020 ・ Sci Rep ・ PMID 33116163
mixed routes
mixed
animal study
Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis.
2020 ・ Exp Brain Res ・ PMID 33052428
inhalation
positive
animal study
Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.
2020 ・ J Clin Biochem Nutr ・ PMID 33041520
inhalation
mixed
human case report
Low-Flow Nasal Cannula Hydrogen Therapy.
2020 ・ J Clin Med Res ・ PMID 33029275
inhalation
positive
animal study
Effects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers.
2020 ・ Med Gas Res ・ PMID 33004708
hydrogen-rich water
positive
human observational study
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