H₂
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reactive oxygen species
774 papers
Delivery-method distribution
hydrogen-rich water: 224
in vitro: 135
inhalation: 133
mixed routes: 118
not specified: 75
injection / infusion: 58
topical application: 14
animal model: 12
hydrogen bath: 5
Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.
2018 ・ Sci Rep ・ PMID 29907804
animal model
positive
animal study
Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.
2018 ・ J Surg Res ・ PMID 29907217
hydrogen-rich water
positive
animal study
Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats.
2018 ・ Med Sci Monit ・ PMID 29875353
inhalation
mixed
animal study
Hydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets FedToxins Contaminated Diets.
2018 ・ Toxins (Basel) ・ PMID 29867031
hydrogen-rich water
positive
animal study
Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitats.
2018 ・ ISME J ・ PMID 29849169
in vitro
not assessed
other
Effect of molecular hydrogen on uterine inflammation during preterm labour.
2018 ・ Biomed Rep ・ PMID 29732148
hydrogen-rich water
positive
animal study
Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.
2018 ・ Free Radic Res ・ PMID 29683360
hydrogen-rich water
mixed
animal study
Hydrogen-rich water mediates redox regulation of the antioxidant system, mycelial regeneration and fruiting body development in Hypsizygus marmoreus.
2018 ・ Fungal Biol ・ PMID 29665957
hydrogen-rich water
positive
in vitro study
[Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury].
2018 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29663991
injection / infusion
positive
animal study
Promising novel therapy with hydrogen gas for emergency and critical care medicine.
2018 ・ Acute Med Surg ・ PMID 29657720
inhalation
not assessed
review
Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs.
2018 ・ Acta Pharmacol Sin ・ PMID 29565041
inhalation
positive
animal study
Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells.
2018 ・ Int J Mol Med ・ PMID 29532858
in vitro
positive
in vitro study
Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision.
2018 ・ J Cell Mol Med ・ PMID 29512923
hydrogen-rich water
positive
human observational study
Inadequate Production of Hby Gut Microbiota and Parkinson Disease.
2018 ・ Trends Endocrinol Metab ・ PMID 29478695
not specified
not assessed
review
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
2018 ・ BMC Cardiovasc Disord ・ PMID 29433438
injection / infusion
positive
animal study
Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen-rich saline in gerbil.
2018 ・ Neurosci Lett ・ PMID 29223865
injection / infusion
positive
animal study
The transfer of hydrogen from inert gas to therapeutic gas.
2017 ・ Med Gas Res ・ PMID 29497488
not specified
not assessed
review
Hydrogen-rich water increases postharvest quality by enhancing antioxidant capacity in Hypsizygus marmoreus.
2017 ・ AMB Express ・ PMID 29264772
hydrogen-rich water
positive
other
Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.
2017 ・ BMC Nephrol ・ PMID 29089029
injection / infusion
positive
animal study
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
2017 ・ Trials ・ PMID 29058596
inhalation
not assessed
human randomized controlled trial
Molecular hydrogen generated by elemental magnesium supplementation alters rumen fermentation and microbiota in goats.
2017 ・ Br J Nutr ・ PMID 28927478
animal model
mixed
animal study
Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
2017 ・ Neuroreport ・ PMID 28926473
inhalation
positive
animal study
Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation.
2017 ・ PLoS One ・ PMID 28902900
injection / infusion
positive
human observational study
Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.
2017 ・ Biochem Biophys Res Commun ・ PMID 28890349
animal model
positive
animal study
Molecular hydrogen increases resilience to stress in mice.
2017 ・ Sci Rep ・ PMID 28852144
inhalation
positive
animal study
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