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Acute effect of hydrogen-rich water on physical, perceptual and cardiac responses during aerobic and anaerobic exercises: a randomized, placebo-controlled, double-blinded cross-over trial.

水素水の急性摂取が有酸素・無酸素運動における身体・知覚・心臓応答に与える影響:無作為化二重盲検クロスオーバー試験

human randomized controlled trial hydrogen-rich water mixed

Abstract

This randomized, double-blind, placebo-controlled crossover study enrolled 22 male amateur middle-distance runners who consumed 500 mL of hydrogen-rich water (HRW) or placebo 30 minutes before exercise testing across 4 days. Aerobic assessments included the Vameval maximal aerobic speed (MAS) test and a time-to-exhaustion (Tlim) protocol, while anaerobic capacity was evaluated via squat jump (SJ), counter-movement jump (CMJ), and five-jump test (5JT). HRW ingestion was associated with improvements in peak heart rate (HRpeak) and rating of perceived exertion (RPE) during both aerobic tests, and Tlim was also extended compared with placebo. However, no statistically significant differences between HRW and placebo were detected for SJ, CMJ, or 5JT performance. These findings suggest that acute HRW consumption may selectively benefit aerobic endurance indices and perceptual responses without meaningfully altering explosive anaerobic output in amateur runners.

Mechanism

Molecular hydrogen dissolved in water is proposed to selectively scavenge reactive oxygen species generated during exercise, thereby reducing oxidative stress and improving cardiorespiratory and perceptual responses during aerobic effort.

Bibliographic

Authors
Jebabli N, Ouerghi N, Abassi W, Yagin FH, Khlifi M, Boujabli M, et al.
Journal
Front Physiol
Year
2023
PMID
38162831
DOI
10.3389/fphys.2023.1240871
PMC
PMC10757640

Tags

Disease:運動・疲労回復 Delivery:水素水経口投与 Mechanism:抗酸化酵素 炎症抑制 酸化ストレス 活性酸素種

Delivery context

Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

Safety notes

Hydrogen-rich water is a low-risk delivery route, but the achievable systemic hydrogen dose is bounded. For clinical applications, inhalation is the most efficient route; inhalation, however, carries explosion risk, and concentration matters (empirical LFL of 10% applies to inhalation environments; high-concentration devices are documented in the Consumer Affairs Agency accident database and are not recommended).

See also:

Other papers on the same disease / condition

Cite as: H2 Papers — PMID 38162831. https://h2-papers.org/en/papers/38162831
Source: PubMed PMID 38162831