-
Hydrogen-rich bath with nano-sized bubbles improves antioxidant capacity based on oxygen radical absorbing and inflammation levels in human serum.
2022 ・ Med Gas Res ・ PMID 34854419
hydrogen bath
positive
human observational study
-
Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice.
2022 ・ Adv Med Sci ・ PMID 34784538
hydrogen-rich water
positive
animal study
-
Hydrogen Promotes the M1 Macrophage Conversion During the Polarization of Macrophages in Necrotizing Enterocolitis.
2021 ・ Front Pediatr ・ PMID 34869093
animal model
positive
animal study
-
Molecular Hydrogen: A Promising Adjunctive Strategy for the Treatment of the COVID-19.
2021 ・ Front Med (Lausanne) ・ PMID 34746162
inhalation
not assessed
review
-
The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury.
2021 ・ BMC Pulm Med ・ PMID 34719405
inhalation
positive
animal study
-
Cell surface sphingomyelin: key role in cancer initiation, progression, and immune evasion.
2021 ・ Lipids Health Dis ・ PMID 34717628
not specified
not assessed
review
-
Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives.
2021 ・ Oxid Med Cell Longev ・ PMID 34646423
mixed routes
not assessed
review
-
Molecular Hydrogen as a Novel Protective Agent against Pre-Symptomatic Diseases.
2021 ・ Int J Mol Sci ・ PMID 34281264
not specified
not assessed
review
-
Homeostatic and endocrine responses as the basis for systemic therapy with medical gases: ozone, xenon and molecular hydrogen.
2021 ・ Med Gas Res ・ PMID 34213500
mixed routes
not assessed
review
-
Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis.
2021 ・ Inflamm Res ・ PMID 33852061
inhalation
positive
animal study
-
Potential Therapeutic Applications of Hydrogen in Chronic Inflammatory Diseases: Possible Inhibiting Role on Mitochondrial Stress.
2021 ・ Int J Mol Sci ・ PMID 33806292
not specified
not assessed
review
-
Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.
2021 ・ Cells ・ PMID 33799840
in vitro
positive
in vitro study
-
Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen.
2021 ・ Sci Rep ・ PMID 33742060
mixed routes
positive
human randomized controlled trial
-
Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota.
2021 ・ J Pain Res ・ PMID 33732014
hydrogen-rich water
positive
animal study
-
Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.
2021 ・ J Surg Res ・ PMID 33639371
inhalation
positive
animal study
-
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
2021 ・ Life Sci ・ PMID 33148420
not specified
not assessed
review
-
Biological Responses to Hydrogen Molecule and its Preventive Effects on Inflammatory Diseases.
2021 ・ Curr Pharm Des ・ PMID 32981496
mixed routes
not assessed
review
-
Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial.
2020 ・ Front Immunol ・ PMID 33324415
hydrogen-rich water
positive
human observational study
-
Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients.
2020 ・ Front Pharmacol ・ PMID 33178011
inhalation
not assessed
review
-
Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury.
2020 ・ Brain Res ・ PMID 32814064
inhalation
positive
animal study
-
Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial.
2020 ・ Sci Rep ・ PMID 32699287
hydrogen-rich water
mixed
human randomized controlled trial
-
Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway.
2020 ・ Int Immunopharmacol ・ PMID 32058932
inhalation
positive
animal study
-
Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
2020 ・ Sci Rep ・ PMID 32029879
mixed routes
positive
human observational study
-
Molecular Hydrogen Metabolism: a Widespread Trait of Pathogenic Bacteria and Protists.
2020 ・ Microbiol Mol Biol Rev ・ PMID 31996394
not specified
not assessed
review
-
Hydrogen water alleviates obliterative airway disease in mice.
2020 ・ Gen Thorac Cardiovasc Surg ・ PMID 31468277
hydrogen-rich water
positive
animal study