immune modulation

180 papers

• Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease.
  2016 ・ Med Gas Res ・ PMID 27867488
  hydrogen-rich water positive human case report
• Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice.
  2016 ・ Oxid Med Cell Longev ・ PMID 27774116
  animal model positive animal study
• Hydrogen-rich Water Exerting a Protective Effect on Ovarian Reserve Function in a Mouse Model of Immune Premature Ovarian Failure Induced by Zona Pellucida 3.
  2016 ・ Chin Med J (Engl) ・ PMID 27647193
  hydrogen-rich water positive animal study
• The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
  2016 ・ Inflammation ・ PMID 27624060
  in vitro positive in vitro study
• Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.
  2016 ・ Oxid Med Cell Longev ・ PMID 27413421
  mixed routes not assessed review
• Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
  2016 ・ Neurochem Res ・ PMID 27386874
  injection / infusion positive animal study
• Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
  2016 ・ J Neuroimmunol ・ PMID 27138092
  hydrogen-rich water positive animal study
• Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
  2016 ・ Brain Res ・ PMID 26826009
  injection / infusion positive animal study
• Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.
  2016 ・ Free Radic Biol Med ・ PMID 26709014
  hydrogen-rich water positive animal study
• MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis.
  2016 ・ FEBS J ・ PMID 26683671
  mixed routes positive animal study
• Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species.
  2016 ・ Biochim Biophys Acta ・ PMID 26488087
  in vitro positive in vitro study
• Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.
  2015 ・ Med Gas Res ・ PMID 26483953
  mixed routes not assessed review
• Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
  2015 ・ Int Immunopharmacol ・ PMID 26253656
  in vitro positive in vitro study
• Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
  2015 ・ J Thorac Cardiovasc Surg ・ PMID 26095621
  hydrogen-rich water positive animal study
• Molecular hydrogen: An inert gas turns clinically effective.
  2015 ・ Ann Med ・ PMID 25936365
  mixed routes not assessed review
• Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.
  2015 ・ Shock ・ PMID 25895142
  in vitro positive in vitro study
• Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells.
  2015 ・ Arch Gynecol Obstet ・ PMID 25681223
  in vitro mixed in vitro study
• Effect of hydrogen-rich water on acute peritonitis of rat models.
  2014 ・ Int Immunopharmacol ・ PMID 24793096
  hydrogen-rich water positive animal study
• Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages.
  2013 ・ Int J Surg ・ PMID 24148794
  in vitro positive in vitro study
• Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.
  2013 ・ Int J Ophthalmol ・ PMID 23826519
  in vitro positive in vitro study
• Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation.
  2013 ・ Int J Radiat Biol ・ PMID 23786587
  in vitro positive in vitro study
• Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: possible treatments targeting the TLR4 pathway.
  2013 ・ Mol Neurobiol ・ PMID 23436141
  not specified not assessed review
• Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis.
  2012 ・ Shock ・ PMID 23160520
  inhalation positive animal study
• Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
  2012 ・ Transpl Int ・ PMID 22891787
  hydrogen-rich water positive animal study
• Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice.
  2012 ・ PLoS One ・ PMID 22860058
  hydrogen-rich water positive animal study