ischemia-reperfusion injury

107 papers

• Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen-rich saline in gerbil.
  2018 ・ Neurosci Lett ・ PMID 29223865
  injection / infusion positive animal study
• Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
  2017 ・ Trials ・ PMID 29058596
  inhalation not assessed human randomized controlled trial
• Protective effects of hydrogen rich water on the intestinal ischemia/reperfusion injury due to intestinal intussusception in a rat model.
  2017 ・ Med Gas Res ・ PMID 28744362
  injection / infusion positive animal study
• Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention.
  2017 ・ Can J Physiol Pharmacol ・ PMID 28350967
  injection / infusion positive animal study
• The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction　- First Pilot Study in Humans.
  2017 ・ Circ J ・ PMID 28321000
  inhalation mixed human observational study
• Molecular hydrogen affords neuroprotection in a translational piglet model of hypoxic-ischemic encephalopathy.
  2016 ・ J Physiol Pharmacol ・ PMID 28011948
  inhalation positive animal study
• Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model.
  2016 ・ Free Radic Biol Med ・ PMID 27789293
  mixed routes positive animal study
• The Clinical Application of Hydrogen as a Medical Treatment.
  2016 ・ Acta Med Okayama ・ PMID 27777424
  mixed routes not assessed review
• Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
  2016 ・ Neurochem Res ・ PMID 27386874
  injection / infusion positive animal study
• Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.
  2016 ・ Shock ・ PMID 26849632
  inhalation positive animal study
• Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
  2016 ・ Brain Res ・ PMID 26705611
  inhalation positive animal study
• Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
  2015 ・ Toxicol Lett ・ PMID 26276082
  in vitro positive in vitro study
• Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.
  2015 ・ Brain Res ・ PMID 25920370
  hydrogen-rich water positive animal study
• A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection).
  2014 ・ Med Gas Res ・ PMID 25671079
  not specified not assessed review
• Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
  2014 ・ Circulation ・ PMID 25366995
  inhalation positive animal study
• Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes.
  2014 ・ Sci Rep ・ PMID 24975958
  mixed routes not assessed animal study
• Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion.
  2014 ・ Free Radic Biol Med ・ PMID 24509162
  hydrogen-rich water positive animal study
• Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
  2013 ・ Free Radic Biol Med ・ PMID 23954468
  hydrogen-rich water positive animal study
• The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion.
  2013 ・ Acta Neurochir Suppl ・ PMID 23564105
  inhalation positive animal study
• A novel method of preserving cardiac grafts using a hydrogen-rich water bath.
  2013 ・ J Heart Lung Transplant ・ PMID 23273745
  hydrogen bath positive animal study
• H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model.
  2012 ・ J Am Heart Assoc ・ PMID 23316300
  inhalation positive animal study
• Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.
  2012 ・ Brain Res ・ PMID 23010312
  injection / infusion positive animal study
• A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level.
  2012 ・ Med Gas Res ・ PMID 22916706
  inhalation positive human case report
• Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
  2012 ・ Oxid Med Cell Longev ・ PMID 22720117
  mixed routes not assessed review
• The principle and the potential approach to ROS-dependent cytotoxicity by non-pharmaceutical therapies: optimal use of medical gases with antioxidant properties.
  2011 ・ Curr Pharm Des ・ PMID 21736540
  not specified not assessed review