mitochondrial function

226 papers

• Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats.
  2026 ・ Naunyn Schmiedebergs Arch Pharmacol ・ PMID 42115396
  hydrogen-rich water positive animal study
• Mitochondrial dysfunction, neuroinflammation, and associated mechanisms in sepsis-associated encephalopathy: from pathogenesis to emerging therapeutics.
  2026 ・ Front Neurosci ・ PMID 42057900
  not specified not assessed review
• Hydrogen gas inhalation alleviated cerebral ischemia/reperfusion injury by regulating mitophagy in SH-SY5Y cells and mice via PTEN-induced kinase 1/Parkin pathway.
  2026 ・ J Stroke Cerebrovasc Dis ・ PMID 42049119
  inhalation positive animal study
• Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms.
  2026 ・ Int J Mol Sci ・ PMID 41977237
  hydrogen-rich water positive animal study
• Molecular hydrogen as a treatment for ME/CFS: a mini-review of clinical evidence and mechanistic rationale.
  2026 ・ Front Med (Lausanne) ・ PMID 41930109
  hydrogen-rich water positive review
• Neuroprotective Effects of Molecular Hydrogen via Oxidative Stress and Neuroinflammation Regulation in a 5xFAD Mouse Model.
  2026 ・ Antioxidants (Basel) ・ PMID 41897548
  inhalation positive animal study
• Molecular hydrogen triggers TRPC4-TRPC4AP-dependent reversible calcium transients via extracellular influx.
  2026 ・ Theranostics ・ PMID 41799190
  inhalation positive in vitro study
• Long-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury.
  2026 ・ Antioxidants (Basel) ・ PMID 41750640
  hydrogen-rich water positive animal study
• The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.
  2026 ・ Eur J Pharmacol ・ PMID 41747800
  mixed routes not assessed review
• Electrolyzed Hydrogen Water Improves Chemosensitivity to Anticancer Drugs by Potently Suppressing Autophagy.
  2026 ・ J Cell Mol Med ・ PMID 41702867
  in vitro positive in vitro study
• H-dependent modulation of tetrahydromethanopterin S-methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei.
  2026 ・ FEBS J ・ PMID 41689349
  in vitro positive in vitro study
• Revisiting molecular hydrogen signaling in mitochondria: Is the Rieske protein the entry point or a downstream sentinel?
  2026 ・ Redox Biol ・ PMID 41496215
  not specified not assessed review
• Medical Gases as Emerging Regulators of Paediatric Endocrine and Neurodevelopmental Pathways: A Mini-Review.
  2026 ・ Acta Paediatr ・ PMID 41482991
  not specified not assessed review
• Sequential hydrogen-release implant for promoting the soft tissue integration through immunomodulatory and pro-remodeling coupling.
  2026 ・ Bioact Mater ・ PMID 41334374
  in vitro positive in vitro study
• Therapeutic potential of magnesium diboride nanosheets in PAH-associated right heart failure: Integrated multi-omics analysis reveals ferroptosis suppression via LC3/ATG5/NCOA4/FTH1 pathway.
  2026 ・ Free Radic Biol Med ・ PMID 41308938
  in vitro positive animal study
• Molecular hydrogen mitigates acetaminophen-induced liver injury and enhances the effects of N-acetylcysteine in diabetic mice.
  2026 ・ J Nutr Biochem ・ PMID 41207540
  hydrogen-rich water positive animal study
• Mechanism by which hydrogen-rich water mitigates exercise-induced fatigue: activation of the immunoresponsive gene 1-itaconate/nuclear factor erythroid 2-related factor 2/heme oxygenase-1 pathway.
  2026 ・ Med Gas Res ・ PMID 40580185
  hydrogen-rich water positive animal study
• Application of Molecular Hydrogen in Early Heart Failure Development: Modulation of Microcirculation, Metabolism, Oxidative Stress, and Myocardial Status.
  2025 ・ Antioxidants (Basel) ・ PMID 41462618
  inhalation positive animal study
• Exploring the Potential of Molecular Hydrogen in Different Heart Failure Models: A Review.
  2025 ・ Int J Mol Sci ・ PMID 41373725
  mixed routes not assessed review
• Molecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy.
  2025 ・ Eur J Med Res ・ PMID 41351127
  inhalation positive animal study
• The Rieske iron-sulfur protein is a primary target of molecular hydrogen.
  2025 ・ Redox Biol ・ PMID 41330217
  mixed routes positive in vitro study
• Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen's Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats.
  2025 ・ Mol Neurobiol ・ PMID 41261203
  injection / infusion positive animal study
• Superoxide- and semiquinone-linked activation of molecular hydrogen in metal-catalyst-free solution.
  2025 ・ Front Mol Biosci ・ PMID 41195421
  in vitro positive in vitro study
• Hydrogen-rich gas enhances mitochondrial membrane potential and respiratory function recovery in Caco-2 cells post-ischemia-reperfusion injury.
  2025 ・ Biochem Biophys Res Commun ・ PMID 41043278
  in vitro positive in vitro study
• Gas as medicine: the case for hydrogen gas as a therapeutic agent for critical illness.
  2025 ・ Intensive Care Med Exp ・ PMID 40938520
  mixed routes not assessed review