-
Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy.
2025 ・ ACS Appl Mater Interfaces ・ PMID 40864154
in vitro
positive
in vitro study
-
Hydrogen promoted mitochondrial autophagy and alleviated CIH-induced vascular endothelial cell senescence by regulating oxidative stress.
2025 ・ Eur J Pharmacol ・ PMID 40845957
animal model
positive
animal study
-
Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models.
2025 ・ Int J Mol Sci ・ PMID 40725167
inhalation
positive
animal study
-
Molecular hydrogen protects against sepsis-induced cardiomyopathy through improving Golgi stress-mediated autophagy, inflammation and apoptosis.
2025 ・ Br J Pharmacol ・ PMID 40717465
inhalation
positive
animal study
-
Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism.
2025 ・ Mol Biol Rep ・ PMID 40705191
inhalation
positive
animal study
-
Acid-triggered ultralong hydrogen release from AB-loaded hollow mesoporous silica nanoparticles enhances salt tolerance in sweetpotato.
2025 ・ J Biotechnol ・ PMID 40651661
in vitro
positive
other
-
Predicting Therapeutic Response to Molecular Hydrogen in Autoimmune Diseases via Immunophenotyping.
2025 ・ APMIS ・ PMID 40590161
hydrogen-rich water
mixed
human observational study
-
Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications.
2025 ・ Mol Biol Rep ・ PMID 40569354
not specified
not assessed
review
-
Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS.
2025 ・ Electromagn Biol Med ・ PMID 40476593
in vitro
positive
in vitro study
-
Redox reactions in chronic pain: mechanisms and relevance in fibromyalgia.
2025 ・ Front Pain Res (Lausanne) ・ PMID 40432823
not specified
not assessed
review
-
Hydrogen-dependent dissimilatory nitrate reduction to ammonium enables growth of Campylobacterota isolates.
2025 ・ ISME J ・ PMID 40367351
in vitro
not assessed
other
-
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
2025 ・ Life Sci Space Res (Amst) ・ PMID 40280637
hydrogen-rich water
positive
animal study
-
Role of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism.
2025 ・ Med Gas Res ・ PMID 40251025
not specified
not assessed
review
-
Hydrogen combined with needle-embedding therapy alleviates traumatic brain injury by inhibiting NLRP3 inflammasome activation via STING signaling pathway.
2025 ・ Cytokine ・ PMID 40187069
mixed routes
positive
animal study
-
Coral calcium hydride promotes peripheral mitochondrial division and reduces AT-II cells damage in ARDS via activation of the Trx2/Myo19/Drp1 pathway.
2025 ・ J Pharm Anal ・ PMID 40177064
mixed routes
positive
animal study
-
Aging, vascular dysfunction, and the blood-brain barrier: unveiling the pathophysiology of stroke in older adults.
2025 ・ Biogerontology ・ PMID 40044939
hydrogen-rich water
not assessed
review
-
Molecular Hydrogen Therapy Enhances Immune Markers in Treg, Plasma, Tr1 Cells, and KLRG1 Expression on Tc Cells: A Case of Acute SDH With Midline Shift and Uncal Herniation Post-decompressive Craniectomy.
2025 ・ In Vivo ・ PMID 40010997
hydrogen-rich water
mixed
human case report
-
Hydrogen-Bonded Organic Framework-Based NIR-II Activated Hydrogen Production for Treatment of Alzheimer's Disease Model Mice.
2025 ・ Small ・ PMID 39989154
in vitro
positive
animal study
-
Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.
2025 ・ PLoS One ・ PMID 39951412
hydrogen-rich water
positive
animal study
-
Hemodialysis employing molecular hydrogen (H) enriched dialysis solution may improve dialysis related fatigue through impact on energy metabolism.
2025 ・ Sci Rep ・ PMID 39934143
injection / infusion
positive
human observational study
-
A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives.
2025 ・ Biochem Biophys Rep ・ PMID 39911528
mixed routes
not assessed
review
-
Oral Administration of Hydrogen-rich Water: Biomedical Activities, Potential Mechanisms, and Clinical Applications.
2025 ・ Curr Pharm Des ・ PMID 39810534
hydrogen-rich water
not assessed
review
-
Molecular hydrogen reduces dermatitis-induced itch, diabetic itch and cholestatic itch by inhibiting spinal oxidative stress and synaptic plasticity via SIRT1-β-catenin pathway in mice.
2025 ・ Redox Biol ・ PMID 39752998
mixed routes
positive
animal study
-
Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
2025 ・ Neurochem Int ・ PMID 39653185
inhalation
positive
animal study
-
Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer's disease: targeting oxidative stress, inflammation, and the gut-brain axis.
2024 ・ Front Aging Neurosci ・ PMID 39839307
hydrogen-rich water
positive
animal study