H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
2012 ・ Biochim Biophys Acta ・ PMID 21621588
mixed routes
not assessed
review
Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
2011 ・ Med Gas Res ・ PMID 22146674
hydrogen-rich water
mixed
human randomized controlled trial
Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
2011 ・ Med Gas Res ・ PMID 22146365
in vitro
positive
in vitro study
Effects of hydrogen-rich water on abnormalities in a SHR.Cg-Leprcp/NDmcr rat - a metabolic syndrome rat model.
2011 ・ Med Gas Res ・ PMID 22146083
hydrogen-rich water
positive
animal study
The 2011 Medical Molecular Hydrogen Symposium: An inaugural symposium of the journal Medical Gas Research.
2011 ・ Med Gas Res ・ PMID 22146082
not specified
not assessed
letter
Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.
2011 ・ Med Gas Res ・ PMID 22146004
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen-rich water attenuates experimental periodontitis in a rat model.
2011 ・ J Clin Periodontol ・ PMID 22092571
hydrogen-rich water
positive
animal study
Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.
2011 ・ J Physiol Anthropol ・ PMID 21963827
hydrogen-rich water
mixed
animal study
Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.
2011 ・ Magn Reson Med Sci ・ PMID 21959999
hydrogen-rich water
positive
animal study
Investigation of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using blood oxygenation level-dependent magnetic resonance imaging.
2011 ・ Jpn J Radiol ・ PMID 21882093
hydrogen-rich water
positive
animal study
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
2011 ・ Am J Physiol Lung Cell Mol Physiol ・ PMID 21764987
mixed routes
positive
animal study
Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water--participation of Pt nanoparticles.
2011 ・ Biosci Biotechnol Biochem ・ PMID 21737933
hydrogen-rich water
mixed
animal study
Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.
2011 ・ Curr Pharm Des ・ PMID 21736547
mixed routes
not assessed
review
The principle and the potential approach to ROS-dependent cytotoxicity by non-pharmaceutical therapies: optimal use of medical gases with antioxidant properties.
2011 ・ Curr Pharm Des ・ PMID 21736540
not specified
not assessed
review
Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
2011 ・ Biochem Biophys Res Commun ・ PMID 21723254
mixed routes
positive
in vitro study
Protective effect of hydrogen-rich saline on decompression sickness in rats.
2011 ・ Aviat Space Environ Med ・ PMID 21702310
injection / infusion
positive
animal study
Therapeutic effects of hydrogen in animal models of Parkinson's disease.
2011 ・ Parkinsons Dis ・ PMID 21687749
not specified
not assessed
review
A possible prevention strategy of radiation pneumonitis: combine radiotherapy with aerosol inhalation of hydrogen-rich solution.
2011 ・ Med Sci Monit ・ PMID 21455114
inhalation
not assessed
letter
Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
2011 ・ J Biomed Biotechnol ・ PMID 21318114
hydrogen-rich water
positive
animal study
Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
2011 ・ Obesity (Silver Spring) ・ PMID 21293445
hydrogen-rich water
positive
animal study
Melatonin-mitochondria interplay in health and disease.
2011 ・ Curr Top Med Chem ・ PMID 21244359
not specified
not assessed
review
Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits.
2011 ・ Brain Res ・ PMID 21195696
inhalation
positive
animal study
Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs.
2011 ・ Neurosci Lett ・ PMID 20888392
hydrogen-rich water
positive
animal study
Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.
2011 ・ Med Hypotheses ・ PMID 20851533
mixed routes
not assessed
other
The hypothesis of an effective safe and novel radioprotective agent: hydrogen-rich solution.
2010 ・ West Indian Med J ・ PMID 21275114
injection / infusion
not assessed
letter
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