H₂
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peroxynitrite scavenging
64 papers
Delivery-method distribution
mixed routes: 26
hydrogen-rich water: 11
not specified: 9
inhalation: 6
in vitro: 5
injection / infusion: 4
topical application: 3
Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo.
2021 ・ J Radiat Res ・ PMID 33231266
mixed routes
positive
animal study
Molecular Hydrogen Application in Stroke: Bench to Bedside.
2021 ・ Curr Pharm Des ・ PMID 32940172
mixed routes
not assessed
review
Hydrogenases and the Role of Molecular Hydrogen in Plants.
2020 ・ Plants (Basel) ・ PMID 32887396
not specified
not assessed
review
Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
2020 ・ PLoS One ・ PMID 32302306
inhalation
positive
animal study
Application of Molecular Hydrogen as a Novel Antioxidant in Sports Science.
2020 ・ Oxid Med Cell Longev ・ PMID 32015786
mixed routes
not assessed
review
A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.
2020 ・ Can J Physiol Pharmacol ・ PMID 31536712
hydrogen-rich water
positive
animal study
Myalgic encephalomyelitis/chronic fatigue syndrome: From pathophysiological insights to novel therapeutic opportunities.
2019 ・ Pharmacol Res ・ PMID 31509764
not specified
not assessed
review
Therapeutic Efficacy of Molecular Hydrogen: A New Mechanistic Insight.
2019 ・ Curr Pharm Des ・ PMID 31057105
not specified
not assessed
review
The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved.
2019 ・ Free Radic Res ・ PMID 30773939
mixed routes
not assessed
review
Molecular hydrogen may enhance the production of testosterone hormone in male infertility through hormone signal modulation and redox balance.
2018 ・ Med Hypotheses ・ PMID 30396494
not specified
not assessed
other
Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage.
2017 ・ Sci Rep ・ PMID 29269749
topical application
positive
animal study
Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
2017 ・ J Clin Biochem Nutr ・ PMID 28751802
mixed routes
not assessed
review
Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
2017 ・ Biochem Biophys Res Commun ・ PMID 28743498
in vitro
positive
in vitro study
Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
2017 ・ Oxid Med Cell Longev ・ PMID 28400915
topical application
positive
animal study
Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
2017 ・ Mol Med Rep ・ PMID 28098910
injection / infusion
positive
animal study
Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.
2017 ・ Redox Rep ・ PMID 26866650
hydrogen-rich water
positive
animal study
Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.
2016 ・ Am J Transl Res ・ PMID 27830032
in vitro
positive
animal study
Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals.
2016 ・ Physiol Res ・ PMID 27643933
mixed routes
not assessed
review
Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats.
2016 ・ Pediatr Pulmonol ・ PMID 26845501
mixed routes
positive
animal study
Treatment with Hydrogen-Rich Saline Delays Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis.
2016 ・ Neurochem Res ・ PMID 26537817
injection / infusion
positive
animal study
Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury.
2015 ・ J Clin Biochem Nutr ・ PMID 26566302
hydrogen-rich water
positive
animal study
Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.
2015 ・ Med Gas Res ・ PMID 26483953
mixed routes
not assessed
review
Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases.
2015 ・ Mol Med Rep ・ PMID 25936373
mixed routes
positive
human case report
Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina.
2015 ・ Clin Exp Ophthalmol ・ PMID 25801048
in vitro
positive
in vitro study
Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
2015 ・ Methods Enzymol ・ PMID 25747486
mixed routes
not assessed
review
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