aging / frailty

37 papers

• Transcriptome-Based Evaluation of Hydrogen Gas Effects for Preventing UVA-Induced Photoaging Using an Artificial Skin Model.
  2026 ・ Geriatr Gerontol Int ・ PMID 41749059
  in vitro positive in vitro study
• Hydrogen promoted mitochondrial autophagy and alleviated CIH-induced vascular endothelial cell senescence by regulating oxidative stress.
  2025 ・ Eur J Pharmacol ・ PMID 40845957
  animal model positive animal study
• The effects of drinking hydrogen-rich water for six weeks on exercise-related biomarkers in exercise-naïve men and women over 50 years following resistance training program: a randomized controlled pilot trial.
  2025 ・ Res Sports Med ・ PMID 40525414
  hydrogen-rich water positive human randomized controlled trial
• Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases.
  2025 ・ Ageing Res Rev ・ PMID 40518021
  mixed routes not assessed review
• Aging, vascular dysfunction, and the blood-brain barrier: unveiling the pathophysiology of stroke in older adults.
  2025 ・ Biogerontology ・ PMID 40044939
  hydrogen-rich water not assessed review
• Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized controlled trial.
  2025 ・ Front Pharmacol ・ PMID 39950118
  inhalation mixed human randomized controlled trial
• Molecular hydrogen inhibits neuroinflammation and ameliorates depressive-like behaviors and short-term cognitive impairment in senescence-accelerated mouse prone 8 mice.
  2025 ・ Behav Brain Res ・ PMID 39522774
  hydrogen-rich water positive animal study
• Hydrogen as an innovative nootropic in health and disease.
  2025 ・ Nutr Health ・ PMID 39042916
  mixed routes not assessed review
• New possibilities of the prevention and treatment of cardiovascular pathologies. the potential of molecular hydrogen in the reduction of oxidative stress and its consequences.
  2024 ・ Physiol Res ・ PMID 39808170
  not specified not assessed review
• Hydrogen-Rich Alkaline Water Supplementation Restores a Healthy State and Redox Balance in HO-Treated Mice.
  2024 ・ Int J Mol Sci ・ PMID 38928440
  hydrogen-rich water positive animal study
• A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.
  2024 ・ Nutrition ・ PMID 38428218
  hydrogen-rich water positive animal study
• Hydrogen Water: Extra Healthy or a Hoax?-A Systematic Review.
  2024 ・ Int J Mol Sci ・ PMID 38256045
  hydrogen-rich water mixed meta-analysis
• Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
  2023 ・ Exp Gerontol ・ PMID 37572992
  inhalation mixed animal study
• Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans.
  2023 ・ Arch Med Sci ・ PMID 37560746
  hydrogen-rich water positive human observational study
• Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity.
  2023 ・ Antioxidants (Basel) ・ PMID 37237854
  mixed routes not assessed review
• Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.
  2023 ・ Geriatr Gerontol Int ・ PMID 36807963
  inhalation positive animal study
• Impact of nutraceuticals and dietary supplements on mitochondria modifications in healthy aging: a systematic review of randomized controlled trials.
  2022 ・ Aging Clin Exp Res ・ PMID 35920994
  mixed routes positive meta-analysis
• Is It a Challenge to Use Molecular Hydrogen for Extending Flower Vase Life?
  2022 ・ Plants (Basel) ・ PMID 35631701
  not specified not assessed review
• Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases.
  2022 ・ Oxid Med Cell Longev ・ PMID 35340218
  mixed routes not assessed review
• Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice.
  2021 ・ J Inflamm Res ・ PMID 34737603
  mixed routes positive animal study
• The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial.
  2021 ・ Exp Gerontol ・ PMID 34601077
  hydrogen-rich water mixed human randomized controlled trial
• Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.
  2020 ・ Int J Mol Sci ・ PMID 33419292
  topical application positive human observational study
• The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report.
  2020 ・ Cent Nerv Syst Agents Med Chem ・ PMID 33167844
  topical application mixed human case report
• A "philosophical molecule," hydrogen may overcome senescence and intractable diseases.
  2020 ・ Med Gas Res ・ PMID 32189669
  inhalation not assessed review
• Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice.
  2020 ・ Chin J Integr Med ・ PMID 31919748
  hydrogen-rich water positive animal study