H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Eumelanin-driven production of molecular hydrogen: A novel element of skin defense?
2015 ・ Med Hypotheses ・ PMID 25920542
not specified
not assessed
other
Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.
2015 ・ Brain Res ・ PMID 25920370
hydrogen-rich water
positive
animal study
Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.
2015 ・ Shock ・ PMID 25895142
in vitro
positive
in vitro study
Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
2015 ・ World J Gastroenterol ・ PMID 25892869
hydrogen-rich water
positive
animal study
Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina.
2015 ・ Clin Exp Ophthalmol ・ PMID 25801048
in vitro
positive
in vitro study
Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
2015 ・ Methods Enzymol ・ PMID 25747486
mixed routes
not assessed
review
Targeting molecular hydrogen to mitochondria: barriers and gateways.
2015 ・ Pharmacol Res ・ PMID 25720951
not specified
not assessed
review
Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.
2015 ・ Mol Cell Biochem ・ PMID 25707580
mixed routes
positive
animal study
Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells.
2015 ・ Arch Gynecol Obstet ・ PMID 25681223
in vitro
mixed
in vitro study
Potential ghrelin-mediated benefits and risks of hydrogen water.
2015 ・ Med Hypotheses ・ PMID 25649854
hydrogen-rich water
not assessed
other
Stimulation of human damaged sperm motility with hydrogen molecule.
2015 ・ Med Gas Res ・ PMID 25649433
in vitro
positive
in vitro study
Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
2015 ・ Shock ・ PMID 25643010
inhalation
positive
animal study
Hydrogen-rich water enhances cadmium tolerance in Chinese cabbage by reducing cadmium uptake and increasing antioxidant capacities.
2015 ・ J Plant Physiol ・ PMID 25543863
in vitro
positive
other
Molecular hydrogen in sports medicine: new therapeutic perspectives.
2015 ・ Int J Sports Med ・ PMID 25525953
mixed routes
not assessed
review
Spinal peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats.
2015 ・ Anesthesiology ・ PMID 25501899
injection / infusion
positive
animal study
A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (part II-comprehensive protection).
2014 ・ Med Gas Res ・ PMID 25671079
not specified
not assessed
review
[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
inhalation
positive
animal study
Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function.
2014 ・ Vasc Health Risk Manag ・ PMID 25378931
hydrogen-rich water
positive
human randomized controlled trial
Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
2014 ・ Circulation ・ PMID 25366995
inhalation
positive
animal study
Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
2014 ・ Brain Res ・ PMID 25251596
inhalation
positive
animal study
Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
2014 ・ PLoS One ・ PMID 25251220
hydrogen-rich water
positive
animal study
Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
2014 ・ Neurosci Res ・ PMID 25196919
inhalation
positive
animal study
Hydrogen protects auditory hair cells from cisplatin-induced free radicals.
2014 ・ Neurosci Lett ・ PMID 25064701
in vitro
positive
in vitro study
Effects of hydrogen-rich water on aging periodontal tissues in rats.
2014 ・ Sci Rep ・ PMID 24985521
hydrogen-rich water
mixed
animal study
Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes.
2014 ・ Sci Rep ・ PMID 24975958
mixed routes
not assessed
animal study
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