H₂
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antioxidant enzymes
423 papers
Delivery-method distribution
hydrogen-rich water: 179
in vitro: 65
inhalation: 48
mixed routes: 47
injection / infusion: 36
not specified: 30
animal model: 8
topical application: 7
hydrogen bath: 3
The Evaluation and Quantitation of Dihydrogen Metabolism Using Deuterium Isotope in Rats.
2015 ・ PLoS One ・ PMID 26103048
mixed routes
positive
animal study
Molecular hydrogen: An inert gas turns clinically effective.
2015 ・ Ann Med ・ PMID 25936365
mixed routes
not assessed
review
Eumelanin-driven production of molecular hydrogen: A novel element of skin defense?
2015 ・ Med Hypotheses ・ PMID 25920542
not specified
not assessed
other
Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
2015 ・ World J Gastroenterol ・ PMID 25892869
hydrogen-rich water
positive
animal study
Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.
2015 ・ Methods Enzymol ・ PMID 25747486
mixed routes
not assessed
review
Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells.
2015 ・ Arch Gynecol Obstet ・ PMID 25681223
in vitro
mixed
in vitro study
Hydrogen-rich water enhances cadmium tolerance in Chinese cabbage by reducing cadmium uptake and increasing antioxidant capacities.
2015 ・ J Plant Physiol ・ PMID 25543863
in vitro
positive
other
[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
2014 ・ Zhonghua Yi Xue Za Zhi ・ PMID 25573317
inhalation
positive
animal study
Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function.
2014 ・ Vasc Health Risk Manag ・ PMID 25378931
hydrogen-rich water
positive
human randomized controlled trial
Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
2014 ・ Brain Res ・ PMID 25251596
inhalation
positive
animal study
Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
2014 ・ Neurosci Res ・ PMID 25196919
inhalation
positive
animal study
Hydrogen protects auditory hair cells from cisplatin-induced free radicals.
2014 ・ Neurosci Lett ・ PMID 25064701
in vitro
positive
in vitro study
Effects of hydrogen-rich water on aging periodontal tissues in rats.
2014 ・ Sci Rep ・ PMID 24985521
hydrogen-rich water
mixed
animal study
Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.
2014 ・ Toxicol Appl Pharmacol ・ PMID 24967689
hydrogen-rich water
positive
animal study
Hydrogen-rich water confers plant tolerance to mercury toxicity in alfalfa seedlings.
2014 ・ Ecotoxicol Environ Saf ・ PMID 24793520
hydrogen-rich water
positive
in vitro study
Effect of hydrogen-rich water on acute peritonitis of rat models.
2014 ・ Int Immunopharmacol ・ PMID 24793096
hydrogen-rich water
positive
animal study
Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats.
2014 ・ Mol Cell Biochem ・ PMID 24652103
hydrogen-rich water
positive
animal study
Hydrogen-rich water delays postharvest ripening and senescence of kiwifruit.
2014 ・ Food Chem ・ PMID 24629944
hydrogen-rich water
positive
other
Energetics and efficiency analysis of a cobaloxime-modified semiconductor under simulated air mass 1.5 illumination.
2014 ・ Phys Chem Chem Phys ・ PMID 24619031
in vitro
not assessed
other
Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.
2014 ・ World J Gastroenterol ・ PMID 24587639
hydrogen-rich water
positive
animal study
Parkinson's disease may be due to failure of melanin in the Substantia Nigra to produce molecular hydrogen from dissociation of water, to protect the brain from oxidative stress.
2014 ・ Med Hypotheses ・ PMID 24529916
not specified
not assessed
other
Hydrogen-rich water regulates cucumber adventitious root development in a heme oxygenase-1/carbon monoxide-dependent manner.
2014 ・ J Plant Physiol ・ PMID 24331413
in vitro
positive
in vitro study
Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.
2014 ・ Hemodial Int ・ PMID 24274030
injection / infusion
positive
human randomized controlled trial
Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells.
2014 ・ J Bone Miner Metab ・ PMID 24196871
in vitro
positive
in vitro study
Ultrathin cellulose film coating of porous alumina membranes for adsorption of superoxide dismutase.
2013 ・ J Mater Chem B ・ PMID 32261187
in vitro
not assessed
in vitro study
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