H₂
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Safety Notes
日本語
cancer radiation (side-effect)
41 papers
Delivery-method distribution
mixed routes: 16
hydrogen-rich water: 11
injection / infusion: 5
inhalation: 4
not specified: 2
in vitro: 2
animal model: 1
Comparison of hydrogen administration methods in the treatment of radiation-induced heart disease in rats.
2026 ・ Can J Physiol Pharmacol ・ PMID 41806364
mixed routes
positive
animal study
Hydrogen-rich water attenuates radiation-induced oral mucositis in mice via antioxidant and gut microbiota-stabilizing effects: a longitudinal study.
2025 ・ Gut Microbes Rep ・ PMID 41909889
hydrogen-rich water
positive
animal study
Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy.
2025 ・ Adv Radiat Oncol ・ PMID 41020280
inhalation
positive
human randomized controlled trial
Molecular Hydrogen as an Antioxidant and Radioprotector: Mechanistic Insights from Monte Carlo Radiation-Chemical Simulations.
2025 ・ Antioxidants (Basel) ・ PMID 41008961
in vitro
positive
other
Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights.
2025 ・ Antioxidants (Basel) ・ PMID 40867844
hydrogen-rich water
positive
animal study
Mechanism of hydrogen-rich water alleviating radiation-induced cognitive impairment through PI3K/AKT/Caspase-9 pathway mediating anti-oxidation.
2025 ・ Mol Cell Biochem ・ PMID 40646375
hydrogen-rich water
positive
animal study
Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water.
2024 ・ Biomed Pharmacother ・ PMID 38906028
hydrogen-rich water
positive
animal study
Prospects of molecular hydrogen in cancer prevention and treatment.
2024 ・ J Cancer Res Clin Oncol ・ PMID 38555538
mixed routes
not assessed
review
Molecular Hydrogen Therapy-A Review on Clinical Studies and Outcomes.
2023 ・ Molecules ・ PMID 38067515
mixed routes
positive
review
Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats.
2023 ・ BMC Mol Cell Biol ・ PMID 37752412
hydrogen-rich water
positive
animal study
Antitumoral Activity of Molecular Hydrogen and Proton in the Treatment of Glioblastoma: An Atypical Pharmacology?
2023 ・ Brain Sci ・ PMID 37626524
inhalation
not assessed
review
Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37375765
not specified
not assessed
review
Hydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application.
2023 ・ Cell Mol Life Sci ・ PMID 37269385
mixed routes
not assessed
review
A Systematic Review of Molecular Hydrogen Therapy in Cancer Management.
2023 ・ Asian Pac J Cancer Prev ・ PMID 36708550
mixed routes
positive
review
Molecular Hydrogen as a Novel Antitumor Agent: Possible Mechanisms Underlying Gene Expression.
2021 ・ Int J Mol Sci ・ PMID 34445428
not specified
not assessed
review
Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study.
2021 ・ Med Gas Res ・ PMID 33942780
inhalation
positive
human observational study
Molecular Hydrogen as a Potential Clinically Applicable Radioprotective Agent.
2021 ・ Int J Mol Sci ・ PMID 33925430
mixed routes
not assessed
review
Antitumor Activity of Protons and Molecular Hydrogen: Underlying Mechanisms.
2021 ・ Cancers (Basel) ・ PMID 33672714
mixed routes
not assessed
review
Protective Effects of Hydrogen against Irradiation.
2021 ・ Curr Pharm Des ・ PMID 33463456
mixed routes
not assessed
review
Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo.
2021 ・ J Radiat Res ・ PMID 33231266
mixed routes
positive
animal study
Molecular hydrogen: A potential radioprotective agent.
2020 ・ Biomed Pharmacother ・ PMID 32763820
mixed routes
not assessed
review
A study on the protective effect of molecular hydrogen on osteoradionecrosis of the jaw in rats.
2020 ・ Int J Oral Maxillofac Surg ・ PMID 32451233
mixed routes
positive
animal study
Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats.
2020 ・ Radiat Res ・ PMID 31634054
hydrogen-rich water
positive
animal study
Regulation of microRNAs by molecular hydrogen contributes to the prevention of radiation-induced damage in the rat myocardium.
2019 ・ Mol Cell Biochem ・ PMID 30830529
hydrogen-rich water
positive
animal study
Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury.
2019 ・ Can J Physiol Pharmacol ・ PMID 30543459
injection / infusion
positive
review
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