H₂
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson's disease: a pilot study.
2021 ・ Neurol Sci ・ PMID 34319514
inhalation
null
human randomized controlled trial
Molecular Hydrogen as a Novel Protective Agent against Pre-Symptomatic Diseases.
2021 ・ Int J Mol Sci ・ PMID 34281264
not specified
not assessed
review
Homeostatic and endocrine responses as the basis for systemic therapy with medical gases: ozone, xenon and molecular hydrogen.
2021 ・ Med Gas Res ・ PMID 34213500
mixed routes
not assessed
review
Molecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway.
2021 ・ Invest Ophthalmol Vis Sci ・ PMID 34196654
mixed routes
positive
animal study
Inhalation of Molecular Hydrogen, a Rescue Treatment for Noise-Induced Hearing Loss.
2021 ・ Front Cell Neurosci ・ PMID 34140880
inhalation
mixed
animal study
Application of hydrogen-rich water modulates physio-biochemical functions and early growth of fragrant rice under Cd and Pb stress.
2021 ・ Environ Sci Pollut Res Int ・ PMID 34114146
hydrogen-rich water
positive
other
Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensalduring gut inflammation.
2021 ・ Elife ・ PMID 34085924
in vitro
not assessed
animal study
Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.
2021 ・ Antioxidants (Basel) ・ PMID 34069398
in vitro
positive
in vitro study
Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
2021 ・ Life Sci ・ PMID 34052293
injection / infusion
positive
animal study
Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study.
2021 ・ Med Gas Res ・ PMID 33942780
inhalation
positive
human observational study
Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4.
2021 ・ Free Radic Res ・ PMID 33929281
in vitro
positive
in vitro study
Molecular Hydrogen as a Potential Clinically Applicable Radioprotective Agent.
2021 ・ Int J Mol Sci ・ PMID 33925430
mixed routes
not assessed
review
Drinking Molecular Hydrogen Water Is Beneficial to Cardiovascular Function in Diet-Induced Obesity Mice.
2021 ・ Biology (Basel) ・ PMID 33922704
hydrogen-rich water
positive
animal study
Protective effects of molecular hydrogen on lung injury from lung transplantation.
2021 ・ Exp Biol Med (Maywood) ・ PMID 33899545
mixed routes
not assessed
review
Effects of hydrogen as adjuvant treatment for unstable angina.
2021 ・ Exp Biol Med (Maywood) ・ PMID 33899541
mixed routes
positive
human randomized controlled trial
Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis.
2021 ・ Inflamm Res ・ PMID 33852061
inhalation
positive
animal study
The protective effect of hydrogen-rich water on rats with type 2 diabetes mellitus.
2021 ・ Mol Cell Biochem ・ PMID 33830396
hydrogen-rich water
positive
animal study
Potential Therapeutic Applications of Hydrogen in Chronic Inflammatory Diseases: Possible Inhibiting Role on Mitochondrial Stress.
2021 ・ Int J Mol Sci ・ PMID 33806292
not specified
not assessed
review
Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.
2021 ・ Cells ・ PMID 33799840
in vitro
positive
in vitro study
Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice.
2021 ・ Int Immunopharmacol ・ PMID 33773206
inhalation
positive
animal study
Inhaled gases as novel neuroprotective therapies in the postcardiac arrest period.
2021 ・ Curr Opin Crit Care ・ PMID 33769417
inhalation
not assessed
review
Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen.
2021 ・ Sci Rep ・ PMID 33742060
mixed routes
positive
human randomized controlled trial
Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota.
2021 ・ J Pain Res ・ PMID 33732014
hydrogen-rich water
positive
animal study
Chemical and Biochemical Aspects of Molecular Hydrogen in Treating Kawasaki Disease and COVID-19.
2021 ・ Chem Res Toxicol ・ PMID 33719401
inhalation
not assessed
review
Downstream Signalling from Molecular Hydrogen.
2021 ・ Plants (Basel) ・ PMID 33672953
hydrogen-rich water
not assessed
review
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