H₂
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apoptosis regulation
280 papers
Delivery-method distribution
mixed routes: 61
hydrogen-rich water: 61
inhalation: 53
in vitro: 47
injection / infusion: 29
not specified: 22
topical application: 5
hydrogen bath: 1
animal model: 1
Novel Role of Molecular Hydrogen: The End of Ophthalmic Diseases?
2023 ・ Pharmaceuticals (Basel) ・ PMID 38004433
mixed routes
not assessed
review
Molecular Hydrogen: Emerging Treatment for Stroke Management.
2023 ・ Chem Res Toxicol ・ PMID 37988743
mixed routes
not assessed
review
Therapeutic Potential of Hydrogen-Rich Water on Muscle Atrophy Caused by Immobilization in a Mouse Model.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37895907
hydrogen-rich water
positive
animal study
Antitumoral Activity of Molecular Hydrogen and Proton in the Treatment of Glioblastoma: An Atypical Pharmacology?
2023 ・ Brain Sci ・ PMID 37626524
inhalation
not assessed
review
Hydrogen-rich saline alleviates cardiomyocyte apoptosis by reducing expression of calpain1 via miR-124-3p.
2023 ・ ESC Heart Fail ・ PMID 37602925
injection / infusion
positive
animal study
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model.
2023 ・ Int Immunopharmacol ・ PMID 37556997
injection / infusion
positive
animal study
Hydrogen Therapy and Its Future Prospects for Ameliorating COVID-19: Clinical Applications, Efficacy, and Modality.
2023 ・ Biomedicines ・ PMID 37509530
mixed routes
not assessed
review
Hydrogen-rich water treatment targets RT1-Db1 and RT1-Bb to alleviate premature ovarian failure in rats.
2023 ・ PeerJ ・ PMID 37397014
hydrogen-rich water
positive
animal study
[Hydrogen-rich water reduces cell damage by reducing excessive autophagy in mouse neuronal cells after oxygen glucose deprivation/reoxygenation].
2023 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 37366131
in vitro
positive
in vitro study
Hydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application.
2023 ・ Cell Mol Life Sci ・ PMID 37269385
mixed routes
not assessed
review
Protective Effect of Hydrogen-Rich Saline on Spinal Cord Damage in Rats.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37111284
injection / infusion
positive
animal study
Molecular Hydrogen: From Molecular Effects to Stem Cells Management and Tissue Regeneration.
2023 ・ Antioxidants (Basel) ・ PMID 36978884
mixed routes
not assessed
review
Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.
2023 ・ Front Public Health ・ PMID 36817910
hydrogen-rich water
positive
animal study
A Systematic Review of Molecular Hydrogen Therapy in Cancer Management.
2023 ・ Asian Pac J Cancer Prev ・ PMID 36708550
mixed routes
positive
review
Taurine, Coenzyme Q, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse.
2023 ・ Hear Res ・ PMID 36577362
hydrogen-rich water
positive
animal study
Two-Dimensional MgSi Nanosheet-Enabled Sustained Hydrogen Generation for Improved Repair and Regeneration of Deeply Burned Skin.
2023 ・ Adv Healthc Mater ・ PMID 36546774
topical application
positive
in vitro study
Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
2023 ・ Int Immunopharmacol ・ PMID 36538853
inhalation
positive
animal study
Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury.
2023 ・ Med Gas Res ・ PMID 36204787
inhalation
positive
animal study
Hydrogen gas and preservation of intestinal stem cells in mesenteric ischemia and reperfusion.
2022 ・ World J Gastrointest Surg ・ PMID 36632117
inhalation
positive
animal study
Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
2022 ・ PLoS One ・ PMID 36574398
injection / infusion
positive
animal study
Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
2022 ・ J Transl Med ・ PMID 36435787
injection / infusion
positive
animal study
Treatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice.
2022 ・ Antioxidants (Basel) ・ PMID 36358525
injection / infusion
positive
animal study
Molecular Hydrogen Reduces Electromagnetic Pulse-Induced Male Rat Reproductive System Damage in a Rodent Model.
2022 ・ Oxid Med Cell Longev ・ PMID 36199428
hydrogen-rich water
positive
animal study
Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing.
2022 ・ Nat Commun ・ PMID 36167814
topical application
positive
animal study
Hydrogen-Rich Water as a Novel Therapeutic Strategy for the Affective Disorders Linked with Chronic Neuropathic Pain in Mice.
2022 ・ Antioxidants (Basel) ・ PMID 36139900
hydrogen-rich water
positive
animal study
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