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intravenous infusion
64 papers
Delivery-method distribution
injection / infusion: 45
mixed routes: 17
not specified: 2
Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis.
2018 ・ Shock ・ PMID 29293174
injection / infusion
positive
animal study
Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen-rich saline in gerbil.
2018 ・ Neurosci Lett ・ PMID 29223865
injection / infusion
positive
animal study
Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.
2017 ・ BMC Nephrol ・ PMID 29089029
injection / infusion
positive
animal study
[Effect of hydrogen-rich water on the CD34 expression in lesion boundary brain tissue of rats with traumatic brain injury].
2017 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 28627348
injection / infusion
positive
animal study
Therapeutic effects of hydrogen on chronic graft-versus-host disease.
2017 ・ J Cell Mol Med ・ PMID 28374556
injection / infusion
positive
animal study
Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
2017 ・ Neuropharmacology ・ PMID 28359771
injection / infusion
positive
animal study
Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.
2017 ・ BMC Musculoskelet Disord ・ PMID 28148301
injection / infusion
positive
animal study
[Effects of hydrogen-rich water on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury].
2016 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29923387
injection / infusion
positive
animal study
The Clinical Application of Hydrogen as a Medical Treatment.
2016 ・ Acta Med Okayama ・ PMID 27777424
mixed routes
not assessed
review
Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis.
2016 ・ Med Sci Monit ・ PMID 27606690
injection / infusion
not assessed
other
Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
2016 ・ Brain Res ・ PMID 26826009
injection / infusion
positive
animal study
Hydrogen-rich saline may be an effective and specific novel treatment for osteoradionecrosis of the jaw.
2015 ・ Ther Clin Risk Manag ・ PMID 26508867
injection / infusion
not assessed
letter
Convenient methods for ingestion of molecular hydrogen: drinking, injection, and inhalation.
safety lineage
2015 ・ Med Gas Res ・ PMID 26504515
mixed routes
not assessed
other
Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise.
2015 ・ Sci Rep ・ PMID 26493164
injection / infusion
positive
animal study
The Evaluation and Quantitation of Dihydrogen Metabolism Using Deuterium Isotope in Rats.
2015 ・ PLoS One ・ PMID 26103048
mixed routes
positive
animal study
Spinal peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats.
2015 ・ Anesthesiology ・ PMID 25501899
injection / infusion
positive
animal study
Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes.
2014 ・ Sci Rep ・ PMID 24975958
mixed routes
not assessed
animal study
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
2014 ・ Int Immunopharmacol ・ PMID 24929023
injection / infusion
positive
human randomized controlled trial
Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush.
2014 ・ PLoS One ・ PMID 24915536
injection / infusion
positive
animal study
Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats.
2014 ・ CNS Neurosci Ther ・ PMID 24685114
injection / infusion
positive
animal study
Hydrogen as a new class of radioprotective agent.
2013 ・ Int J Biol Sci ・ PMID 24155664
mixed routes
not assessed
review
Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity.
2013 ・ Med Gas Res ・ PMID 23816239
injection / infusion
positive
human case report
Protective effects of hydrogen-rich saline on ulcerative colitis rat model.
2013 ・ J Surg Res ・ PMID 23773716
injection / infusion
positive
animal study
Lactulose mediates suppression of dextran sodium sulfate-induced colon inflammation by increasing hydrogen production.
2013 ・ Dig Dis Sci ・ PMID 23371012
mixed routes
positive
animal study
Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress.
2012 ・ Chin Med J (Engl) ・ PMID 22800834
injection / infusion
positive
animal study
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