H₂
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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism.
2025 ・ Mol Biol Rep ・ PMID 40705191
inhalation
positive
animal study
Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications.
2025 ・ Adv Sci (Weinh) ・ PMID 40619605
mixed routes
not assessed
review
Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.
2025 ・ Antioxidants (Basel) ・ PMID 40563361
topical application
positive
human case report
Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS.
2025 ・ Electromagn Biol Med ・ PMID 40476593
in vitro
positive
in vitro study
Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.
2025 ・ Sci Rep ・ PMID 40410340
hydrogen-rich water
positive
animal study
Molecular Hydrogen in the Treatment of Respiratory Diseases.
2025 ・ Int J Mol Sci ・ PMID 40362357
mixed routes
not assessed
review
Role and mechanism of molecular hydrogen in the treatment of Parkinson's diseases.
2025 ・ Front Neurosci ・ PMID 40336538
mixed routes
mixed
review
Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application.
2025 ・ MedComm (2020) ・ PMID 40297245
mixed routes
not assessed
review
Coral calcium hydride promotes peripheral mitochondrial division and reduces AT-II cells damage in ARDS via activation of the Trx2/Myo19/Drp1 pathway.
2025 ・ J Pharm Anal ・ PMID 40177064
mixed routes
positive
animal study
Molecular hydrogen: Mechanism against oxidative stress and application in periodontitis: A review.
2025 ・ Medicine (Baltimore) ・ PMID 40068089
mixed routes
not assessed
review
Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.
2025 ・ Clin Cosmet Investig Dermatol ・ PMID 40061044
mixed routes
not assessed
review
Hydrogen-Bonded Organic Framework-Based NIR-II Activated Hydrogen Production for Treatment of Alzheimer's Disease Model Mice.
2025 ・ Small ・ PMID 39989154
in vitro
positive
animal study
A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives.
2025 ・ Biochem Biophys Rep ・ PMID 39911528
mixed routes
not assessed
review
Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model.
2025 ・ Antioxidants (Basel) ・ PMID 39857445
hydrogen-rich water
positive
animal study
Oral Administration of Hydrogen-rich Water: Biomedical Activities, Potential Mechanisms, and Clinical Applications.
2025 ・ Curr Pharm Des ・ PMID 39810534
hydrogen-rich water
not assessed
review
Molecular hydrogen gas and its therapeutic potential in recent disease progression.
2025 ・ Med Gas Res ・ PMID 39436178
not specified
not assessed
review
Emerging role of antioxidants in Alzheimer's disease: Insight into physiological, pathological mechanisms and management.
2024 ・ Pharm Sci Adv ・ PMID 41550171
not specified
not assessed
review
New possibilities of the prevention and treatment of cardiovascular pathologies. the potential of molecular hydrogen in the reduction of oxidative stress and its consequences.
2024 ・ Physiol Res ・ PMID 39808170
not specified
not assessed
review
Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model.
2024 ・ Antioxidants (Basel) ・ PMID 39594470
inhalation
positive
animal study
Mitigating environmental toxicity with hydrogen nanobubbles: A mitochondrial function-based approach to ecological restoration.
2024 ・ Environ Int ・ PMID 39515037
in vitro
positive
in vitro study
Perspective targeted diagnosis and therapy of mitochondrial bioenergetics across different diagnoses.
2024 ・ Bratisl Lek Listy ・ PMID 39487838
not specified
not assessed
review
Inhalation of H/O(66.7 %/33.3 %) mitigates depression-like behaviors in diabetes mellitus complicated with depression mice via suppressing inflammation and preventing hippocampal damage.
2024 ・ Biomed Pharmacother ・ PMID 39405908
inhalation
positive
animal study
Au/Ag@ZnS yolk-shell photocatalysts enhanced with noble metals and hyaluronic acid for efficient hydrogen production in rheumatoid arthritis therapy.
2024 ・ Int J Biol Macromol ・ PMID 39322151
in vitro
positive
in vitro study
Using oral molecular hydrogen supplements to combat microinflammation in humans: a pilot observational study.
2024 ・ Int J Med Sci ・ PMID 39310256
hydrogen-rich water
positive
human observational study
Hydrogen-releasing magnesium hydrogel mitigates post laminectomy epidural fibrosis through inhibition of neutrophil extracellular traps.
2024 ・ Acta Biomater ・ PMID 39260811
in vitro
positive
animal study
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