H₂
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apoptosis regulation
280 papers
Delivery-method distribution
mixed routes: 61
hydrogen-rich water: 61
inhalation: 53
in vitro: 47
injection / infusion: 29
not specified: 22
topical application: 5
hydrogen bath: 1
animal model: 1
Gas as medicine: the case for hydrogen gas as a therapeutic agent for critical illness.
2025 ・ Intensive Care Med Exp ・ PMID 40938520
mixed routes
not assessed
review
Nanobiocatalyst-Driven Spatiotemporal Hydrogen Delivery Induces Dormancy Potentiated Catalytic Tumor Therapy.
2025 ・ ACS Nano ・ PMID 40931918
in vitro
positive
in vitro study
Immunomodulatory Effects of Molecular Hydrogen Therapy in Systemic Lupus Erythematosus With Pericarditis and Pleuritis: A Case Report.
2025 ・ In Vivo ・ PMID 40877145
not specified
mixed
human case report
Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy.
2025 ・ ACS Appl Mater Interfaces ・ PMID 40864154
in vitro
positive
in vitro study
Molecular hydrogen protects against sepsis-induced cardiomyopathy through improving Golgi stress-mediated autophagy, inflammation and apoptosis.
2025 ・ Br J Pharmacol ・ PMID 40717465
inhalation
positive
animal study
Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism.
2025 ・ Mol Biol Rep ・ PMID 40705191
inhalation
positive
animal study
Mechanism of hydrogen-rich water alleviating radiation-induced cognitive impairment through PI3K/AKT/Caspase-9 pathway mediating anti-oxidation.
2025 ・ Mol Cell Biochem ・ PMID 40646375
hydrogen-rich water
positive
animal study
Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications.
2025 ・ Adv Sci (Weinh) ・ PMID 40619605
mixed routes
not assessed
review
Molecular Hydrogen Therapy in Rheumatoid Arthritis: A Case Report on the Amelioration of Methotrexate-induced Myelosuppression and Immune Modulation.
2025 ・ In Vivo ・ PMID 40579028
not specified
positive
human case report
Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications.
2025 ・ Mol Biol Rep ・ PMID 40569354
not specified
not assessed
review
Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases.
2025 ・ Ageing Res Rev ・ PMID 40518021
mixed routes
not assessed
review
Local Visible-Photocatalytic Production of Hydrogen and Warm Heat for Combination Treatment of Pressure Ulcer.
2025 ・ Adv Sci (Weinh) ・ PMID 40491331
topical application
positive
animal study
Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS.
2025 ・ Electromagn Biol Med ・ PMID 40476593
in vitro
positive
in vitro study
Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis.
2025 ・ Biomaterials ・ PMID 40411985
hydrogen-rich water
positive
animal study
Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.
2025 ・ Sci Rep ・ PMID 40410340
hydrogen-rich water
positive
animal study
Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.
2025 ・ BMC Chem ・ PMID 40405232
inhalation
positive
animal study
Molecular Hydrogen in the Treatment of Respiratory Diseases.
2025 ・ Int J Mol Sci ・ PMID 40362357
mixed routes
not assessed
review
Role and mechanism of molecular hydrogen in the treatment of Parkinson's diseases.
2025 ・ Front Neurosci ・ PMID 40336538
mixed routes
mixed
review
Hydrogen combined with needle-embedding therapy alleviates traumatic brain injury by inhibiting NLRP3 inflammasome activation via STING signaling pathway.
2025 ・ Cytokine ・ PMID 40187069
mixed routes
positive
animal study
Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.
2025 ・ Clin Cosmet Investig Dermatol ・ PMID 40061044
mixed routes
not assessed
review
Molecular Hydrogen Therapy Enhances Immune Markers in Treg, Plasma, Tr1 Cells, and KLRG1 Expression on Tc Cells: A Case of Acute SDH With Midline Shift and Uncal Herniation Post-decompressive Craniectomy.
2025 ・ In Vivo ・ PMID 40010997
hydrogen-rich water
mixed
human case report
Performance of Unmodified Mechanical Ventilators With 2% Hydrogen Gas Mixtures.
2025 ・ Respir Care ・ PMID 39969918
inhalation
not assessed
other
Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.
2025 ・ PLoS One ・ PMID 39951412
hydrogen-rich water
positive
animal study
A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives.
2025 ・ Biochem Biophys Rep ・ PMID 39911528
mixed routes
not assessed
review
Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model.
2025 ・ Antioxidants (Basel) ・ PMID 39857445
hydrogen-rich water
positive
animal study
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