H₂
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intravenous infusion
64 papers
Delivery-method distribution
injection / infusion: 45
mixed routes: 17
not specified: 2
Hydrogen Molecule Delivery System to Ischemic Intestine Using Resuscitative Endovascular Balloon Occlusion of Aorta in Hemorrhagic Shock-A Proof-of-Concept Study.
2026 ・ Biomedicines ・ PMID 41751354
injection / infusion
positive
animal study
Acoustic hydrogen delivery to treat PANoptosis induced by myocardial ischemia/reperfusion injury in rats.
2026 ・ Biomater Adv ・ PMID 41671925
injection / infusion
positive
animal study
Advances in hydrogen delivery strategies for therapeutic applications.
2026 ・ Adv Drug Deliv Rev ・ PMID 41232804
mixed routes
not assessed
review
Four-dimensional data independent acquisition proteomics and metabolomics reveal mechanisms of hydrogen-rich water at Zusanli (ST36) point against triple-negative breast cancer in mice.
2025 ・ J Tradit Chin Med ・ PMID 41376217
injection / infusion
positive
animal study
Hemodialysis employing molecular hydrogen (H) enriched dialysis solution may improve dialysis related fatigue through impact on energy metabolism.
2025 ・ Sci Rep ・ PMID 39934143
injection / infusion
positive
human observational study
The Landscape of Smart Biomaterial-Based Hydrogen Therapy.
2024 ・ Adv Sci (Weinh) ・ PMID 39166484
mixed routes
not assessed
review
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
2024 ・ Sci Rep ・ PMID 38745034
mixed routes
positive
animal study
Effect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: anstudy.
2023 ・ Front Pharmacol ・ PMID 38638334
mixed routes
null
animal study
Hydrogen-rich saline alleviates cardiomyocyte apoptosis by reducing expression of calpain1 via miR-124-3p.
2023 ・ ESC Heart Fail ・ PMID 37602925
injection / infusion
positive
animal study
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
2023 ・ Theranostics ・ PMID 37215568
mixed routes
positive
animal study
Protective Effect of Hydrogen-Rich Saline on Spinal Cord Damage in Rats.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37111284
injection / infusion
positive
animal study
Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils.
2022 ・ PLoS One ・ PMID 36574398
injection / infusion
positive
animal study
Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
2022 ・ J Transl Med ・ PMID 36435787
injection / infusion
positive
animal study
Evaluation of the hydrogen-rich water alleviation potential on mercury toxicity in earthworms using ATR-FTIR and LC-ESI-MS/MS spectroscopy.
2022 ・ Environ Sci Pollut Res Int ・ PMID 34718956
injection / infusion
positive
animal study
Protective effects of molecular hydrogen on lung injury from lung transplantation.
2021 ・ Exp Biol Med (Maywood) ・ PMID 33899545
mixed routes
not assessed
review
Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities.
2021 ・ Curr Pharm Des ・ PMID 32962610
mixed routes
positive
review
Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.
2021 ・ Ann Thorac Surg ・ PMID 32649946
injection / infusion
positive
animal study
Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
2020 ・ Mol Med Rep ・ PMID 31746358
injection / infusion
positive
animal study
Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
2020 ・ Prog Neuropsychopharmacol Biol Psychiatry ・ PMID 31629777
injection / infusion
positive
animal study
Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.
2019 ・ PLoS One ・ PMID 31574107
injection / infusion
positive
animal study
Micro/Nanomaterials-Augmented Hydrogen Therapy.
2019 ・ Adv Healthc Mater ・ PMID 31267691
mixed routes
not assessed
review
[Different types of molecular hydrogen donors and their pharmacokinetics in vivo].
2019 ・ Sheng Li Xue Bao ・ PMID 31008498
mixed routes
not assessed
review
[Research progress of hydrogen-rich saline for eye diseases].
2018 ・ Zhonghua Yan Ke Za Zhi ・ PMID 30107657
injection / infusion
not assessed
review
[Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury].
2018 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29663991
injection / infusion
positive
animal study
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
2018 ・ BMC Cardiovasc Disord ・ PMID 29433438
injection / infusion
positive
animal study
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